Modest Improvements of Survival for Patients with Small Cell Lung Cancer Aged 45 to 59 Years Only, Diagnosed in the Netherlands, 1989 to 2008

Janssen‐Heijnen, M.L.G.; Karim‐Kos, Henrike E.; Drift, Miep A. van der; Groen, Harry J.M.; Ho, Vincent K.Y.; Koning, Caro C.E.; Vries, Esther de

doi:10.1097/jto.0b013e3182370e4c

Cited by 18 publications

(21 citation statements)

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“…In cases where an eligible study contained no numerical survival estimates but presented one or more graphs showing survival by age group stratified by another characteristics (eg, sex, stage at diagnosis), SP emailed the corresponding author to request numerical data. [16][17][18][19][20][21] SP and HG independently assessed the quality of included studies against selected evaluation domains from the QUIPS tool: 22 study participation; prognostic factor measurement; outcome measurement; and statistical reporting. We adapted the items within each domain to our study.…”

Section: Data Collection Process and Data Itemsmentioning

confidence: 99%

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

et al. 2021

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ObjectivesTo identify patterns of age disparities in cancer survival, using colon and lung cancer as exemplars.DesignSystematic review of the literature.Data sourcesWe searched Embase, MEDLINE, Scopus and Web of Science through 18 December 2020.Eligibility criteriaWe retained all original articles published in English including patients with colon or lung cancer. Eligible studies were required to be population-based, report survival across several age groups (of which at least one was over the age of 65) and at least one other characteristic (eg, sex, treatment).Data extraction and synthesisTwo independent reviewers extracted data and assessed the quality of included studies against selected evaluation domains from the QUIPS tool, and items concerning statistical reporting. We evaluated age disparities using the absolute difference in survival or mortality rates between the middle-aged group and the oldest age group, or by describing survival curves.ResultsOut of 3047 references, we retained 59 studies (20 for colon, 34 for lung and 5 for both sites). Regardless of the cancer site, the included studies were highly heterogeneous and often of poor quality. The magnitude of age disparities in survival varied greatly by sex, ethnicity, socioeconomic status, stage at diagnosis, cancer site, and morphology, the number of nodes examined and treatment strategy. Although results were inconsistent for most characteristics, we consistently observed greater age disparities for women with lung cancer compared with men. Also, age disparities increased with more advanced stages for colon cancer and decreased with more advanced stages for lung cancer.ConclusionsAlthough age is one of the most important prognostic factors in cancer survival, age disparities in colon and lung cancer survival have so far been understudied in population-based research. Further studies are needed to better understand age disparities in colon and lung cancer survival.PROSPERO registration numberCRD42020151402.

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Section: Data Collection Process and Data Itemsmentioning

confidence: 99%

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

et al. 2021

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“…Several studies have reported an improvement in survival after the introduction of chemotherapy in the 1970s (Janssen‐Heijnen et al., 2012). Despite numerous clinical trials, systemic treatment for patients with SCLC has not changed significantly in the past several decades (Byers & Rudin, 2015; Pietanza, Byers, Minna, & Rudin, 2015).…”

Section: Introductionmentioning

confidence: 99%

Real‐world treatment patterns and outcomes of patients with extensive disease small cell lung cancer

et al. 2020

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“…The surprisingly good survival of patients with lung cancer may, however, be associated with a specific substructure of histopathological types noted in patients entering treatment, notably an underrepresentation of small-cell lung cancers. Other jurisdictions did not show much progress in improving the prognosis of individuals with lung cancer, with lower scores occurring in cohorts with greater representation of this kind of lung cancer [ 24 , 25 ]. Similar issues complicated a uniform interpretation of brain tumour therapeutic outcomes, as the registries generally do not include ICD-10 subcategory codes.…”

Section: Discussionmentioning

confidence: 99%

Availability and outcomes of radiotherapy in Central Poland during the 2005-2012 period - an observational study

et al. 2015

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BackgroundUsing a cross-database integrative approach, we performed an epidemiological analysis in a representative region of central Poland to evaluate the availability of radiotherapy (RTx) and overall survival of adult patients undergoing RTx for cancer.MethodsEpidemiological data on cancer incidence in the 2005–2012 period were obtained from the Nationwide Cancer Registry. Using data from the Ministry of Internal Affairs, we collected survival information of all patients treated in the only centre providing RTx for a region inhabited by approximately 2.6 million people.ResultsAfter filtering out individuals on the basis of exclusion criteria, the final dataset covered 17,736 patients. Availability of RTx increased marginally, from 23.5% (2005) to 24.4% (2011, R = 0.39, p = 0.38), with the highest values noted in patients with cervical (78.5%), prostate (70.6%) and breast cancer (62.7%). However, due to the decreasing population of the region, we noted increasing disparity in the likelihood of receiving RTx depending on the patient’s area of residence, with rural areas becoming progressively more neglected. The best prognosis was noted among patients with breast or prostate cancer with 5-year OS rates reaching 81.2% and 83.3%, respectively. Multivariate analysis controlling for type of diagnosis and patient age showed a time-dependent improvement in outcomes (HR(95% CI): 0.96(0.94-0.98); p < 0.0001).ConclusionsAvailability of RTx in Poland is still below that reported by developed European centres. Survival of patients undergoing radical RTx has gradually improved, although it is still below that of leading RTx departments, potentially due to delayed diagnosis or organisational barriers, necessitating further investigations.Electronic supplementary materialThe online version of this article (doi:10.1186/s12885-015-1236-7) contains supplementary material, which is available to authorized users.

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Modest Improvements of Survival for Patients with Small Cell Lung Cancer Aged 45 to 59 Years Only, Diagnosed in the Netherlands, 1989 to 2008

Cited by 18 publications

References 54 publications

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Patterns of age disparities in colon and lung cancer survival: a systematic narrative literature review

Real‐world treatment patterns and outcomes of patients with extensive disease small cell lung cancer

Availability and outcomes of radiotherapy in Central Poland during the 2005-2012 period - an observational study

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