Modern wound care for the poor: a randomized clinical trial comparing the vacuum system with conventional saline-soaked gauze dressings

Negative Pressure Wound Therapy Decreases Mortality in a Murine Model of Burn-Wound Sepsis Involving Pseudomonas aeruginosa Infection

“…WTD is a basic treatment for burn wounds, and many fundamental studies and clinical investigations have used WTD as a control group [11], [31]–[33]. In addition to WTD, nano-silver dressings, hydrogel dressings, and biological dressings are also widely used in the treatment of burn wounds.…”

Debridement of Chronic Wounds

“…25 This study found that the homemade NPWT system significantly reduced healing time compared with traditional salinesoaked dressings. The homemade NPWT group received radical surgical debridement before therapy, whereas the control group received debridement if clinically indicated.…”

“…[21][22][23][24][25][26] The first, published in 2000, examined the time to satisfactory healing and the change in wound surface area among the two modalities in the healing of surgically debrided diabetic foot wounds. 22 Results showed that satisfactory healing, calculated from the date of initial debridement to the date of definitive closure, was achieved in approximately half the time in the NPWT group, and a decrease in wound surface area was seen in the NPWT group compared with an increase in wound surface area in the saline-moistened gauze group.…”

A Multicenter Randomized Controlled Trial Comparing Treatment of Venous Leg Ulcers Using Mechanically Versus Electrically Powered Negative Pressure Wound Therapy

“…23 However, several other RCTs that include VLUs patients have demonstrated superior healing with NPWT. [15][16][17]23,[32][33][34] In addition to RCT data, there have been a number of retrospective comparison studies and case series that have demonstrated excellent results using NPWT for the treatment of refractory venous ulcers.…”