Modern Trends in Management of Mooren’s Ulcer

Abstract

BACKGROUNDMooren's ulcer is a chronic peripheral corneal ulceration featuring conjunctival immunoglobulin deposits. It is considered as the result of a limbic immune process with hyperactivation of T and B lymphocytes. The exact aetiology remains unknown. The response to topical steroid therapy, immunosuppressants and surgical procedures is usually poor and the visual outcome can be devastating. We report our good results in managing these cases with 3 days of intravenous methylprednisolone and 3-7 months of cyclosporine eyedrops.