Modern trends in fluid therapy for burns

Tricklebank, Stephen

doi:10.1016/j.burns.2008.09.007

Cited by 111 publications

(82 citation statements)

References 100 publications

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“…Fluids constitute the most important health-related intervention in patients with moderate to severe burns [1] [2]. Therefore, centers managing these cases use different models for resuscitation [3] [4] [5].…”

Section: Introductionmentioning

confidence: 99%

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Habib¹,

Saadah²,

Al-Samerrae³

et al. 2017

MPS

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Objective: Evaluation of the effect of Ringer Lactate, as the resuscitative burn fluid according to Parkland Formula, on restoring the levels of body electrolytes and proteins. Design: A retrospective cohort study. Setting: The National Burns Unit, Mafraq Hospital, Abu Dhabi, United Arab Emirates (UAE). Patients: One hundred and fifteen patients admitted with fresh burns between 1st of January 2011 and 31st of December 2013, who met inclusion and exclusion criteria. Methods: Team collected demographic and clinical data for each patient using a standard form. Patients received Ringer Lactate solely as the resuscitative burn fluid according to Parkland Formula. Baseline (pre-) and third-day (post-) variables included levels of sodium, potassium, chloride, proteins, and albumin. Researchers then performed paired comparisons of serum electrolytes and protein levels. Results: Mean values showed maintenance of the potassium and chloride levels within the normal range after administering the Ringer Lactate, significant decline in sodium, and a marked hypoproteinaemia and hypoalbuminaemia post-resuscitation. Conclusions: Ringer Lactate used as the mere resuscitative post burn fluid is suboptimal. Sodium supplementation may be required to correct hyponatremia. Colloids, preferably intravenous albumin should be added, as advised by the original Parkland Formula.

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Section: Introductionmentioning

confidence: 99%

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Habib¹,

Saadah²,

Al-Samerrae³

et al. 2017

MPS

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“…The ‘rule of ten’ estimated fluid requirements to be somewhere between the modified Brooke and Parkland formulae 87.8% of the time 43. In research conducted at the United States Army Institute of Surgical Research (USAISR), the use of this formula along with hourly urine output in a decision support algorithm improved burn resuscitation significantly 44 45. The ‘rule of ten’ is likely to be adopted as a NATO standard in the near future.…”

Section: Discussionmentioning

confidence: 99%

Should early amputation impact initial fluid therapy algorithms in burns resuscitation? A retrospective analysis using 3D modelling

et al. 2016

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This study demonstrated that amputation can have an unpredictable effect on burn size that results in a significant deviation from predicted fluid resuscitation volumes. This discrepancy in fluid estimation may cause iatrogenic complications due to over-resuscitation in burn-injured casualties. Combining a more accurate estimation of postamputation burn size with goal-directed fluid therapy during the resuscitation phase should enable burn care teams to optimise patient outcomes.

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“…Edema is particularly evident in burn injuries where there can be massive transvascular flux of fluids and where fluid resuscitation strategies can further compound tissue edema. 31 Pressure and shear forces applied to the wound can also lead to direct deformational damage to the wound as well as capillary closure leading to cellular disruption and microvascular damage arising from ischemia-reperfusion injury. 32 Scarring and the eventual mechanical properties of the healed wound are influenced by the extrinsic mechanical forces that are applied to the wound during proliferation and remodeling.…”

Section: Factors Affecting Wound Healingmentioning

confidence: 99%

Review of near-infrared methods for wound assessment

Sowa

Kuo²,

et al. 2016

J. Biomed. Opt

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Modern trends in fluid therapy for burns

Cited by 111 publications

References 100 publications

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Should early amputation impact initial fluid therapy algorithms in burns resuscitation? A retrospective analysis using 3D modelling

Review of near-infrared methods for wound assessment

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