Modern Measles

En glemt pioner

“…50 000; en nedgang på over 90 % (9). I løpet av de første 20 årene etter at meslingvaksinen ble satt i produksjon, har man anslått at vaksinen forhindret 52 millioner sykdomstilfeller og 5 200 dødsfall (10).…”

Chickenpox, Measles, and Mumps

“…Still another pattern of infection has been observed in extremely isolated regions of the world, where whole populations may never have experienced measles before its exogenous introduction. In a classic description of such an epidemic in the Faroe Islands in 1846, measles was observed to spread rapidly through an entire population, regardless of age, with an attack rate of virtually 100% [403]. Mortality rates tend to be higher in populations having little experience with measles.…”

“…Mortality rates tend to be higher in populations having little experience with measles. An extreme example is the Fiji Islands epidemic of 1875, in which 20,000 people, or about one fourth of the population, are said to have died [403].…”

“…From 1920-1950 in Massachusetts, deaths caused by measles declined progressively during each successive 5-year period from 7.6 to 0.28 per 100,000 people, despite an approximately constant morbidity related to measles [403]. Because the decline preceded the widespread use of antibiotics, much of the change is attributed to improved social conditions: less crowding, improved nutrition, and medical care.…”

Measles Virus Infection: Mechanisms of Immune Suppression

“…Koplik's spots appearing as discrete, tiny, gray-white papules on a dull-red base on the buccal mucosa, usually appear 1 day before the onset of rash and persist for 2 or 3 days (Suringa et al, 1970). Koplik's spots have been reported in 60%-70% of patients with measles but are probably present in most persons who develop measles (Babbott & Gordon, 1954). Photophobia from iridocyclitis, sore throat, headache, abdominal pain, and generalized mild lymphadenopathy are also common.…”