Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis

Andronikou, Savvas; Wieselthaler, Nicky

doi:10.1007/s00247-004-1236-2

Cited by 84 publications

(79 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Contrast-enhanced MRI is generally considered to be superior to CT in detecting and assessing CNS tuberculosis (16,80,100,142). While MRI is arguably superior to CT in identifying meningeal and parenchymal abnormalities, its limited availability worldwide and the requirement for general anesthesia in children suggest that it may have a limited impact on TBM diagnosis globally (5).…”

Section: Radiographic Assessmentsmentioning

confidence: 99%

Central Nervous System Tuberculosis: Pathogenesis and Clinical Aspects

et al. 2008

View full text Add to dashboard Cite

SUMMARY Tuberculosis of the central nervous system (CNS) is a highly devastating form of tuberculosis, which, even in the setting of appropriate antitubercular therapy, leads to unacceptable levels of morbidity and mortality. Despite the development of promising molecular diagnostic techniques, diagnosis of CNS tuberculosis relies largely on microbiological methods that are insensitive, and as such, CNS tuberculosis remains a formidable diagnostic challenge. Insights into the basic neuropathogenesis of Mycobacterium tuberculosis and the development of an appropriate animal model are desperately needed. The optimal regimen and length of treatment are largely unknown, and with the rising incidence of multidrug-resistant strains of M. tuberculosis, the development of well-tolerated and effective antibiotics remains a continued need. While the most widely used vaccine in the world largely targets this manifestation of tuberculosis, the BCG vaccine has not fulfilled the promise of eliminating CNS tuberculosis. We put forth this review to highlight the current understanding of the neuropathogenesis of M. tuberculosis, to discuss certain epidemiological, clinical, diagnostic, and therapeutic aspects of CNS tuberculosis, and also to underscore the many unmet needs in this important field.

show abstract

Section: Radiographic Assessmentsmentioning

confidence: 99%

Central Nervous System Tuberculosis: Pathogenesis and Clinical Aspects

et al. 2008

View full text Add to dashboard Cite

show abstract

“…Therefore the imaging studies are very important and they should include a detailed and meticulous ultrasound and an intravenous urography for enhanced calyceal visualization. Characteristic US signs we have to look for are: echogenic calyces and mixed or echo-free areas in the site of the pyramids, which suggest cavitations (21,22). In the first two cases US revealed right nephromegalia with hyperechoic sinus and left nephromegalia with hypoechoic areas respectively.…”

Section: Discussionmentioning

confidence: 99%

Genitourinary tuberculosis in children - a diagnostic challenge

Duicu¹,

Mărginean²,

Kiss³

et al. 2013

Romanian Review of Laboratory Medicine

View full text Add to dashboard Cite

show abstract

“…The upper half of the doughnut is made up of the aortic arch Table 4. Contribution of lymph node groups to defined zones on sagittal CT (and by inference on lateral CXR) using only true positives (see Table 3 and the main pulmonary arteries, 11,12 which is the reason why we have defined the region below the right upper lobe bronchus for evaluation in our methodology.…”

Section: Discussionmentioning

confidence: 99%