Modern diagnostic capabilities for vasospastic angina diagnostics (intracoronary provocative testing)

Обединский, А. А.; Бугуров, С. В.; Крестьянинов, О. В.; Нарышкин, И. А.; Зубарев, Д. Д.; Grazhdankin, Igor; Ибрагимов, Р. У.; Байструков, В. И.; Найденов, Р. А.; Кретов, Е. И.

doi:10.21688/1681-3472-2017-1-98-103

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…Стоит отметить, что в японской популяции частота встречаемости вазоспазма намного выше, чем у европеоидов. По данным японских исследователей, среди больных стенокардией в Японии вазоспастическая форма ставится в 40% случаев [2]. Достоверных статистических данных по Российской Федерации в настоящее время нет.…”

Section: список сокращенийunclassified

Clinical Patterns of Vasospastic Angina

Ульбашева

Намитоков

Кандинский

et al. 2018

Kompleks. probl. serdečno-sosud. zabol.

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Vasospastic angina (angina inversa, variant angina or Prinzmetal angina) is a rare variant of the course of coronary artery disease. Despite a good understanding of its underlying mechanisms (prolonged coronary spasm resulting from endothelial dysfunction) and contributing factors (smoking, exposure to cold weather, cocaine, autoimmune diseases, etc.), the treatment of each individual patient remains a source of discussion. To date, these patients are commonly treated with drugs, especially calcium antagonists and nitrates. The article presents clinical cases of patients with vasospastic angina and discusses their treatment depending on the individual clinical pattern. Early diagnosis of vasospastic angina allows preventing in some cases fatal complications and save patients’ life.

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Section: список сокращенийunclassified

Clinical Patterns of Vasospastic Angina

Ульбашева

Намитоков

Кандинский

et al. 2018

Kompleks. probl. serdečno-sosud. zabol.

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Capecitabine and vasospastic angina: a clinical case

et al. 2022

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The article presents a clinical case of a 78-year-old female patient with a clinical picture of vasospastic angina during the capecitabin treatment. The issues under discussion include difficulties of diagnosing vasospastic angina, a potential danger and incidence of coronary vasospastic reactions during chemotherapy with drugs of this group, and current approaches to prevention and correction of fluoropyrimidine cardiotoxicity. The presented clinical case confirms that vasospasm is a manifestation of capecitabin cardiotoxicity. This case also illustrates the importance of interaction and co-ordination of the work of oncologists and cardiologists at all stages of care of oncological patients.

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Differential diagnosis of angina pectoris in the practice of the regional vascular center: a clinical observation

et al. 2022

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The leading cause of myocardial ischemia in case of coronary atherosclerosis and coronary vasospasm combination in one patient is difficult to establish. However, it is important to know for optimal treatment strategy: choosing between beta-blockers and calcium channel blockers as a preferred treatment, need for percutaneous coronary intervention. We present a case of a 56-yearold patient who was admitted with acute coronary syndrome without ST-segment elevation, low Killip class, and low GRACE score. Stress echocardiography revealed inducible transmural myocardial ischemia (regional wall motion abnormalities and ST segment elevation on the ECG) accompanied by polymorphic ventricular tachycardia. The coronary angiography showed single-vessel moderate stenosis in the left anterior descending artery. There were no changes in comparison with previous angiography. The patient was considered to have vasospastic angina. A probable mechanism is coronary artery spasm at the site of the atherosclerotic plaque. The article is discussed the difficulties in diagnosing vasospastic angina, especially in the presence of borderline stenosis in the coronary artery. We reviewed similar cases and discussed the difficulties of a vasospastic angina diagnosis especially in the presence of moderate coronary artery stenosis, the role of the provocative tests, and the pharmacological management. Demonstrating, discussing and analyzing cases of patients with a combined mechanism of myocardial ischemia is substantiated for further improving their diagnosis and treatment.

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Modern diagnostic capabilities for vasospastic angina diagnostics (intracoronary provocative testing)

Cited by 4 publications

References 29 publications

Clinical Patterns of Vasospastic Angina

Clinical Patterns of Vasospastic Angina

Capecitabine and vasospastic angina: a clinical case

Differential diagnosis of angina pectoris in the practice of the regional vascular center: a clinical observation

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