Modern Concepts of the Pathogenesis of Polycystic Ovary Syndrome (Literature Review)

Abstract

FEATURES OF LIPID PEROXIDATION PROCESS IN NORMAL CONDITIONS AND IN VARIOUS PATHOLOGICAL CONDITIONS IN CHILDREN (REVIEW OF LITERATURE)Gavrilova O.A. Установлено, что 95-98 % используемого орга-низмом кислорода идёт на выработку энергии и окис-лительный катаболизм субстратов, то есть на реак-ции окислительного фосфорилирования [5]. Из всего объёма только 5 % кислорода используется на синтез активных форм кислорода (АФК): супероксидного Scientific Centre for Family Health and Human Reproduction Problems (664003, Irkutsk, ul. Timiryazeva, 16, Russian Federation) The article presents literature data on the lipid peroxidation and antioxidant defense system (LPO-AOD) under normal conditions. Lipid peroxidation is a physiological process which is constantly occurring in cell membranes and has a chain, free-radical mechanism. Free-radical reactions are involved in the repair of cell membranes, in the processes of phagocytosis and destruction of microorganisms, in conducting nerve impulses, in metabolism of various xenobiotics by liver and in biosynthesis of