Modern approaches to the creation of 2D and 3D cellular models for the study of lung fibrosis
A. E. Tolstoluzhinskaya,
N. A. Basalova,
A. Y. Efimenko
Abstract:Lung fibrosis is a consequence of many influences leading to damage to lung tissue and the development of subsequent inflammation. Fibrosis is an overgrowth of connective tissue, which can lead to a violation of the architectonics of the lungs and reduce their functionality up to a fatal outcome. At the same time, the mechanisms underlying fibrogenesis are currently insufficiently studied. In this regard, the task of studying them does not lose its relevance, and its solution requires the development of models… Show more
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