Moderate Treadmill Exercise Improves Spinal Cord Injury Repair Administered with Carica Papaya Leaf Extract-Loaded Nanocomposite Hydrogel

Abstract

In the current research, spinal cord injury was repaired through a moderate treadmill exercise and carica papaya leaf extract-loaded nanocomposite hydrogel. In vitro studies showed that the carica papaya extract-loaded nanocomposite hydrogel augmented the metabolic function of the cells and showed a gradual degradation. In vivo study showed that the developed treatment strategy promoted spinal cord injury repair as shown in histopathological studies and BBB assay.