Moderate alcohol consumption predicts long-term mortality in elderly subjects with chronic heart failure

Abstract

Our data demonstrates that moderate alcohol consumption is associated with an increased long-term mortality risk in the elderly in the presence of CHF.

Alcohol Consumption and Risk of Death in Male Physicians With Heart Failure

“…10 Gargiulo and colleagues examined the effects of moderate wine consumption on risk of death in a cohort of elderly individuals from southern Italy. Moderate alcohol consumption was defined as <250 ml/day, which is approximately 2 glasses per day.…”

“…A recent European study showed a 29% increase in long-term mortality with moderate alcohol intake in older participants with previously diagnosed HF. 10 However, this study only included wine drinkers and only evaluated ≤250 ml/day of alcohol intake. 10 Thus, in the current study we examined whether alcohol consumption and type of alcoholic beverage consumed are associated with mortality in US male physicians with prevalent HF.…”

Alcohol dependence and physical comorbidity: Increased prevalence but reduced relevance of individual comorbidities for hospital-based mortality during a 12.5-year observation period in general hospital admissions in urban North-West England

“…We explain this finding primarily from the fact that individuals with AD compared to controls had a substantial excess of physical comorbidities. Physical morbidity and its relevance for mortality in AD is determined by the complex interrelationship of the following main factors: acute detrimental organ effects of bingeing and alcohol poisoning; long term alcohol-related organ effects that appear in the late, chronic stage of severe and recurrent AD; increased likelihood of infectious diseases; increased likelihood of potentially life-threatening multisystem dysfunction as each type of a physical comorbidity may contribute to develop the other; a multitude of AD related behavioral and lifetime changes such as tobacco use, illicit drug consumption, lack of physical activity, and poor nutrition which all interfere with self-care and raise the risk of premature death once physical illness emerges [17,21,23,36,69,70].…”

Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts

“…Several studies have shown a positive relationship between aging and chronic heart failure (Shioi and Inuzuka 2012;Piccirillo et al 2013). The pathogenic factors of CVDs include smoking habits, alcohol consumption, and lack of exercise, especially in the elder population (Blondon et al 2013;Fernhall 2013;Gargiulo et al 2013).…”