Abstract-This paper describes a system, referred to as MESSL, for separating and localizing multiple sound sources from an underdetermined reverberant two-channel recording. By clustering individual spectrogram points based on their interaural phase and level differences, MESSL generates masks that can be used to isolate individual sound sources. We first describe a probabilistic model of interaural parameters that can be evaluated at individual spectrogram points. By creating a mixture of these models over sources and delays, the multi-source localization problem is reduced to a collection of single source problems. We derive an expectation maximization algorithm for computing the maximum-likelihood parameters of this mixture model, and show that these parameters correspond well with interaural parameters measured in isolation. As a byproduct of fitting this mixture model, the algorithm creates probabilistic spectrogram masks that can be used for source separation. In simulated anechoic and reverberant environments, separations using MESSL produced on average a signal-to-distortion ratio 1.6 dB greater and PESQ results 0.27 mean opinion score units greater than four comparable algorithms.