Modelling the Feline Leukemia Virus (FeLV) in Natural Populations of Cats (Felis catus)

Fromont, Emmanuelle

doi:10.1006/tpbi.1997.1320

Cited by 34 publications

(51 citation statements)

References 31 publications

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“…As α and µ are not always precisely estimated, we studied the sensitivity of the model to α and µ (mortality rates of FIV and FeLV, respectively) through simulations. The non-sensitivity of the model to these parameters has been observed, and was also previously demonstrated in the models of viruses taken separately (Courchamp et al 1995a;Fromont et al 1997b). We will thus use values commonly accepted in the literature, that is 0.2 for α and 0.5 for µ (see Courchamp et al 1995a;Fromont et al 1997b).…”

Section: (B) Application To Biological Datasupporting

confidence: 58%

“…The material and methods used in this paper have been more fully described in previous works (Courchamp et al 1995a;Fromont et al 1997b). We will thus be concise concerning the description of the viruses, the host and the construction of the model.…”

Section: Methodsmentioning

confidence: 99%

“…Individuals that do not become naturally immunized become persistently viraemic and die within an average of two years from various proliferative or immunosuppressive disorders. This mortality rate (0.5) will be used in this model (Fromont et al 1997b). Almost 80% of infected pregnant females abort or give birth to viraemic kittens that die within weeks to months.…”

Section: (B) Virusesmentioning

confidence: 99%

“…The model combined two previous models: one describing the dynamics of FIV in cat populations (Courchamp et al 1995a), the second describing FeLV dynamics in cat populations (Fromont et al 1997b). These models were based on the work of Anderson & May (e.g.…”

Section: Introductionmentioning

confidence: 99%

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Dynamics of two feline retroviruses (FIV and FeLV) within one population of cats

Courchamp

Suppo

Fromont

et al. 1997

Proc. R. Soc. Lond. B

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We present a deterministic model of the dynamics of two microparasites simultaneously infecting a single host population. Both microparasites are feline retroviruses, namely Feline Immunodeficiency Virus (FIV) and Feline Leukaemia Virus (FeLV). The host is the domestic cat Felis catus. The model has been tested with data generated by a long-term study of several natural cat populations. Stability analysis and simulations show that, once introduced in a population, FIV spreads and is maintained, while FeLV can either disappear or persist. Moreover, introduction of both viruses into the population induces an equilibrium state for individuals of each different pathological class. The viruses never induce the extinction of the population. Furthermore, whatever the outcome for the host population (persistence of FIV only, or of both viruses), the global population size at the equilibrium state is only slightly lower than it would have been in the absence of the infections (i.e. at the carrying capacity), indicating a low impact of the viruses on the population. Finally, the impact of the diseases examined simultaneously is higher than the sum of the impact of the two diseases examined separately. This seems to be due to a higher mortality rate when both viruses infect a single individual.

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Section: (B) Application To Biological Datasupporting

confidence: 58%

Section: Methodsmentioning

confidence: 99%

Section: (B) Virusesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dynamics of two feline retroviruses (FIV and FeLV) within one population of cats

Courchamp

Suppo

Fromont

et al. 1997

Proc. R. Soc. Lond. B

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“…Feline leukemia virus may strongly limit populations (Courchamp and Sugihara, 1999). Cat populations were depressed by 7-20% in a population model with only 4.3-12.4% FeLV prevalence (Fromont et al, 1997). The cat population on Mauna Kea may be depressed by feline diseases, but their presence suggests they would not be effective agents in a biological control strategy.…”

mentioning

confidence: 99%