Modelling the effect of hydration on skin conductivity

Davies, Luke; Chappell, P.H.; Melvin, T.

doi:10.1111/srt.12344

Cited by 11 publications

(10 citation statements)

References 24 publications

(35 reference statements)

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“…Skin impedance is an important facet of bio-impedance and can be used to analyze the condition of the human body. Its measurement can feed back physiological information about the skin, such as skin hydration [ 5 ], the thickness of the stratum corneum [ 6 , 7 ], the condition of water channels through the skin [ 8 , 9 ], and so on. In addition, electrode–skin impedance is a significant factor in the application of other bioimpedance parameters, such as heart rate measurement, which greatly affects the target signal quality [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Review of Stratum Corneum Impedance Measurement in Non-Invasive Penetration Application

Wang

Zhao

et al. 2018

Biosensors

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Due to advances in telemedicine, mobile medical care, wearable health monitoring, and electronic skin, great efforts have been directed to non-invasive monitoring and treatment of disease. These processes generally involve disease detection from interstitial fluid (ISF) instead of blood, and transdermal drug delivery. However, the quantitative extraction of ISF and the level of drug absorption are greatly affected by the individual’s skin permeability, which is closely related to the properties of the stratum corneum (SC). Therefore, measurement of SC impedance has been proposed as an appropriate way for assessing individual skin differences. In order to figure out the current status and research direction of human SC impedance detection, investigations regarding skin impedance measurement have been reviewed in this paper. Future directions are concluded after a review of impedance models, electrodes, measurement methods and systems, and their applications in treatment. It is believed that a well-matched skin impedance model and measurement method will be established for clinical and point-of care applications in the near future.

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Section: Introductionmentioning

confidence: 99%

Review of Stratum Corneum Impedance Measurement in Non-Invasive Penetration Application

Wang

Zhao

et al. 2018

Biosensors

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“…Change in skin conductance from baseline also remained consistent across all interface volumes. Previous studies have associated skin conductance with skin hydration levels, which in this research could be further associated with the interface volumes of interaction stimuli that may cause such hydration changes ( 56 ). Change in skin conductance from baseline also remained consistent across the application sequence, showing that there was no significant cumulative change in skin conductance across stimuli and therefore unlikely to be a change in skin hydration.…”

Section: Discussionmentioning

confidence: 96%

The role of friction on skin wetness perception during dynamic interactions between the human index finger pad and materials of varying moisture content

Merrick

Rosati

Filingeri

2022

Journal of Neurophysiology

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Mechanosensory inputs arising from dynamic interactions between the skin and moisture, such as when sliding a finger over a wet substrate, contribute to the perception of skin wetness. Yet, the exact relationship between the mechanical properties of a wet substrate, such as friction, and the resulting wetness perception, remains to be established under naturalistic haptic interactions. We modelled the relationship between mechanical and thermal properties of substrates varying in moisture levels (0.49x10-4; 1.10x10-4; 2.67x10-4 ml mm-2), coefficient of friction (0.783, 0.848, 1.033, 0.839, 0.876, 0.763), and maximum thermal transfer rate (Qmax, ranging from 511 to 1260 W m-2 K-1), and wetness perception arising from the index finger pad's contact with such substrates. Forty young participants (20M/20F) performed dynamic interactions with 21 different stimuli using their index finger pad at a controlled angle, pressure, and speed. Participants rated their wetness perception using a 100 mm visual analogue scale (very dry to very wet). Partial least squares regression analysis indicated that coefficient of friction explained only ~11% of the variance in wetness perception, while Qmax and moisture content accounted for ~22% and 18% of the variance, respectively. These parameters shared positive relationships with wetness perception, such that the greater the Qmax, moisture content, and coefficient of friction, the wetter the perception experienced. We found no differences in wetness perception between males and females. Our findings indicate that while the friction of a wet substrate modulates wetness perception, it is still secondary to thermal parameters such as Qmax.

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“…Bio‐impedance analysis (RJL Systems, Clinton Township, Michigan) was performed using the two‐electrode method as previously described on AHSC‐treated areas, native skin, and STSG‐treated areas to assess water content, oil content, and pliability. Briefly, electrodes are placed 4 cm apart in the region of skin to be tested with time‐varying sinusoidal 1 V applied in a 200 Ω resistance circuit with voltage drop measured with current passage less than 10 μA . Differences between means were measured using two‐way analysis of variance with a Tukeys post‐hoc test with a P ‐value of <0.05 considered as significant.…”

Section: Methodsmentioning

confidence: 99%

“…Briefly, electrodes are placed 4 cm apart in the region of skin to be tested with time-varying sinusoidal 1 V applied in a 200 Ω resistance circuit with voltage drop measured with current passage less than 10 μA. [11][12][13][14] Differences between means were measured using two-way analysis of variance with a Tukeys post-hoc test with a P-value of <0.05 considered as significant.…”

Section: Wound Healing and Functional Tissue Assessmentmentioning

confidence: 99%

In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing

Granick

Baetz²,

Labroo³

et al. 2019

International Wound Journal

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A new cell‐tissue technology uses a patient's skin to create an in vivo expanding and self‐organising full‐thickness skin autograft derived from potent cutaneous appendages. This autologous homologous skin construct (AHSC) is manufactured from a small full‐thickness skin harvest obtained from an uninjured area of the patient. All the harvested tissue is incorporated into the AHSC including the endogenous regenerative cellular populations responsible for skin maintenance and repair, which are activated during the manufacturing process. Without any exogenous supplementation or culturing, the AHSC is swiftly returned to the patient's wound bed, where it expands and closes the defect from the inside out with full‐thickness fully functional skin. AHSC was applied to a greater than two‐year old large (200 cm2) chronic wound refractory to multiple failed split‐thickness skin grafts. Complete epithelial coverage was achieved in 8 weeks, and complete wound coverage with full‐thickness functional skin occurred in 12 weeks. At 6‐month follow‐up, the wound remained covered with full‐thickness skin, grossly equivalent to surrounding native skin qualitatively and quantitatively equivalent across multiple functions and characteristics, including sensation, hair follicle morphology, bio‐impedance and composition, pigment regeneration, and gland production.

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Modelling the effect of hydration on skin conductivity

Cited by 11 publications

References 24 publications

Review of Stratum Corneum Impedance Measurement in Non-Invasive Penetration Application

Review of Stratum Corneum Impedance Measurement in Non-Invasive Penetration Application

The role of friction on skin wetness perception during dynamic interactions between the human index finger pad and materials of varying moisture content

In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing

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