Agricultural biotechnologies have the potential to offer higher incomes for farmers in developing countries and lower-priced and better-quality food, feed and fibre. That potential is being heavily compromised, however, because of strict regulatory systems in the European Union and elsewhere governing transgenically modified (GM) crops. This paper examines why the EU has taken the extreme opposite policy position on GM food to equally affluent North America, what has been the impact on developing country welfare of the limited adoption of GM crop varieties so far, and what impact GM adoption by developing countries themselves could have on their economic welfare.