Modelling Parasite Transmission and Control

doi:10.1007/978-1-4419-6064-1

Cited by 7 publications

(1 citation statement)

References 415 publications

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“…In the long term the spread of diseases to new areas (infectious and parasitic diseases spread through the air, water, soil, and food) caused by climate factors will become a serious problem (Michael, Spear, 2010). To avert this threat the environmental services market needs to be developed, in particular medical and biological monitoring.…”

Section: Figure 2 Environmental Management: Challenges and Opportunitiesmentioning

confidence: 99%

The Future of the Natural Resources Sector in Russia

Касимов

Alekseeva

Chulok

et al. 2015

International Journal of Social Ecology and Sustainable Development

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Environmental management, technologies, products and services are commonly expected to provide significant economic opportunities for companies and countries. This is mainly due to increasing awareness among politicians, academics and the wider population on the importance of environmental aspects in daily life. Consequently demand for environmentally friendly solutions is expected to grow continuously in the next decade. The present study is part of a broader research project which examines the long-term science and technology (S&T) agenda in Russia up to 2030. The project's results were approved by the Prime Minister of Russia in early January 2014. Researchers from the National Research University Higher School of Economics carried out the research project at the request of the Russian Ministry of Education and Science between 2011 and 2013. The research comprised six interrelated spheres: ICT; biotechnology, medicine and public health; new materials and nanotechnologies; environmental management; transport and space systems; and energy efficiency and energy conservation. For each sphere, the project explored in-depth the global emergent challenges and opportunities, the risks, and their degree of influence on Russia. The authors analysed the most important potential market niches, products and services that are capable of radically shaping world markets and highlighted their competitive advantages. Within the framework of these priority science areas authors emphasised several spheres of particular potential value and compared the level of research carried out in Russia and the leading countries. The current paper also covers the analyses the natural resources sector made within a project aimed at integration of national and sectoral S&T Foresight studies funded by the Russian Ministry of Education and Science. Findings show that the potential applications for environmental products and services are manifold. The study is based on a thorough analysis of expert opinions and their assessment of future applications and the development of demand for these applications. However the authors note that the expert opinions included in the assessment of prospective products, services and markets, despite being based on rigorous assessment, still reflect expectations. Their opinions incorporate a degree of uncertainty especially with regard to how and when (or whether) the markets, technologies, products and services will develop in the expected ways.

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Section: Figure 2 Environmental Management: Challenges and Opportunitiesmentioning

confidence: 99%

The Future of the Natural Resources Sector in Russia

Касимов

Alekseeva

Chulok

et al. 2015

International Journal of Social Ecology and Sustainable Development

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Natural and human induced factors influencing the abundance of Schistosoma host snails in Zambia

Monde

Syampungani

Brink

2016

Environ Monit Assess

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Schistosomiasis remains a global public health problem affecting about 240 million people. In Zambia, 2 million are infected while 3 million live with the risk of getting infected. Research and interventions relating to schistosomiasis are mainly linked to disease epidemiology. Malacological and ecological aspects of the disease are superficially understood. Developing effective control measures requires an understanding of interacting environmental and socioeconomic factors of host snails vis-a-vis schistosomiasis. Therefore, the present work involved collecting social and environmental data in a large field study in two zones in Zambia that are different in terms of temperature and rainfall amounts. Social data collected through questionnaires included demographic, educational and knowledge of schistosomiasis disease dynamics. Environmental data included physicochemical factors, aquatic plants and snails. Gender (P < 0.001) significantly influences livelihood strategies, while age (P = 0.069) and level of education (P = 0.086) have a moderate influence in zone I. In zone III, none of these factors (age, P = 0.378; gender, P = 0.311; education, P = 0.553) play a significant role. Environmental parameters explained 43 and 41 % variation in species composition for zones I and III, respectively. Most respondents’ (52 %, 87 %) perception is that there are more cases of bilharzia in hot season than in other seasons (rainy season 23 %, 7 %; cold season 8 %, 0 % and year round 17 %, 6 %) for zone I and zone III, respectively.Electronic supplementary materialThe online version of this article (doi:10.1007/s10661-016-5351-y) contains supplementary material, which is available to authorized users.

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A bite to fight: front-line innate immune defenses against malaria parasites

Tannous

Ghanem

2018

Pathogens and Global Health

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Malaria infection caused by Plasmodium parasites remains a major health burden worldwide especially in the tropics and subtropics. Plasmodium exhibits a complex life cycle whereby it undergoes a series of developmental stages in the Anopheles mosquito vector and the vertebrate human host. Malaria severity is mainly attributed to the genetic complexity of the parasite which is reflected in the sophisticated mechanisms of invasion and evasion that allow it to overcome the immune responses of both its invertebrate and vertebrate hosts. In this review, we aim to provide an updated, clear and concise summary of the literature focusing on the interactions of the vertebrate innate immune system with Plasmodium parasites, namely sporozoites, merozoites, and trophozoites. The roles of innate immune factors, both humoral and cellular, in anti-Plasmodium defense are described with particular emphasis on the contribution of key innate players including neutrophils, macrophages, and natural killer cells to the clearance of liver and blood stage parasites. A comprehensive understanding of the innate immune responses to malaria parasites remains an important goal that would dramatically help improve the design of original treatment strategies and vaccines, both of which are urgently needed to relieve the burden of malaria especially in endemic countries.

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Modelling Parasite Transmission and Control

Cited by 7 publications

References 415 publications

The Future of the Natural Resources Sector in Russia

The Future of the Natural Resources Sector in Russia

Natural and human induced factors influencing the abundance of Schistosoma host snails in Zambia

A bite to fight: front-line innate immune defenses against malaria parasites

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