Abstract. The monitoring of activated sludge processes is difficult because of their slow dynamics, the complexity of their behavior. To obtain the desired level of performance in an activated sludge system, a proper balance must be maintained between aeration (energy consumption) and the quantity of sludge recirculation. The objective of this study is to determine the necessary amount of recirculated sludge in activated sludge process in the aim to reduce the energy consumption with respect of environmental standards. To achieving this objective, a comparative study between three models was performed. In order to reduce the complexity of activated-sludge process, the first is a linear model based on principal component analysis method (PCA), the second is an Adaptive Neural Fuzzy Inference System model (ANFIS), while the third is based on coupling of those two approaches. The best values of validation criterion obtained with the last method show the high performance of the hybrid model proposed...