Modelling lipid metabolism in plants: a slippery problem?

Harwood, John L.; Ramli, Umi Salamah; Page, Rachel; Quant, Patti A.

doi:10.1042/bst0270285

Cited by 6 publications

(1 citation statement)

References 5 publications

(6 reference statements)

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“…We first published on the use of TDCA in plants as part of a session organized by the Biochemical Society (Harwood et al, 1999) and, later, as part of my Society of Chemical Industry International Lecture Award. They were later referred to in a review article about olive and other fruits (Salas et al, 2000) and then, in more detail, with reference to oil palm and olive fruits (Ramli et al, 2002a, b).…”

Section: Metabolic Control Analysismentioning

confidence: 99%

Working with Randy: The Diacylglycerol Acyltransferase Story

Harwood

2020

Lipids

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Vegetable oils are one of the main agricultural commodities. Demand has been increasing steadily over the last five decades and, with finite land available, it is vital that we increase productivity. My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylglycerol acyltransferase (DGAT) as important at regulating carbon flux during oil accumulation. This led to collaborations with Randy Weselake's research group when we quantified the importance of DGAT in oilseed rape by using flux control analysis. Later, with David Taylor, we showed that over-expression of DGAT boosted oil accumulation in field-grown crops by around 8%. These studies led to a multitude of experiments with different oil crops, such as oil palm and soybean, as well as many rewarding collaborations with Randy.

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Section: Metabolic Control Analysismentioning

confidence: 99%