“…In the last decade, most emphasis has been given to the development of reliable process models, based on a first principles approach as well as a data driven approach (empirical correlations). For example, specific models for chemical and biochemical processes (Potocnik & Grabec, 1999;Soejima et al, 2008;Singh et al, 2009a;Charalampopoulos et al, 2009), pharmaceutical processes (Westerhuis et al, 1997;Wu et al, 2005: Zhou et al, 2005Jia & Williams, 2007;Singh et al, 2009b), and food processes (Zwietering & Hasting, 1997;Otero & Sanz, 2003, Mittal, 2007González-Sáiz et al, 2009) have been developed successfully. Process models are extensively used for different applications, for instance, in process optimization and control (Fu & Barford, 1993;Sen & Srinivasa Babu, 2005;Kawohl et al, 2007;Nagy, 2007;Pintaric & Kravanja, 2008;Ashoori et al, 2009;Papadopoulos & Seferlis, 2009).…”