Modelling and simulation for fabrication of 3D printed polymeric porous tissue scaffolds

Sahai, Nitin; Saxena, Kuldeep K.; Gogoi, Manashjit

doi:10.1080/2374068x.2020.1728643

Cited by 21 publications

(9 citation statements)

References 15 publications

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“…This powder form offers distinct advantages in various industrial applications due to its high surface area, reactivity, and ease of handling. One prominent application of La2O3 powder is in the production of ceramic materials [34][35][36][37]. When mixed with other oxides and subjected to high temperatures, lanthanum oxide powder acts as a sintering aid, facilitating the formation of dense and durable ceramic structures.…”

Section: Primary Reinforcement Particlementioning

confidence: 99%

“…The novelty of this approach lies in its innovative combination of La2O3 reinforcement and FSP fabrication technique, offering a novel pathway towards developing lightweight, high-strength aluminum composites tailored for various demanding applications [31][32][33][34]. Through comprehensive characterization and analysis, this study seeks to elucidate the microstructural evolution, mechanical behavior, and performance optimization strategies of La2O3-reinforced aluminum composites fabricated via FSP, contributing valuable insights to the field of advanced materials engineering and manufacturing [36].…”

Section: Introductionmentioning

confidence: 99%

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Advancements in Aluminum-Based Composite Manufacturing: Leveraging La2O3 Reinforcement through Friction Stir Process

Kareem,

Raju,

et al. 2024

E3S Web of Conf.

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This study investigates the advancements in Aluminum-Based Composite Manufacturing through the incorporation of lanthanum oxide (La2O3) reinforcement using the Friction Stir Process (FSP). The pivotal role of precision machining, particularly the vertical milling machine, in executing FSP is emphasized. Specific parameters, including pin diameter, tool tilt angle, and rotational speed, were meticulously selected to ensure optimal performance. The uniform distribution of La2O3 particles within the composite matrix highlights the effectiveness of the fabrication process, indicating proper mixing and dispersion techniques. Experimental findings reveal significant improvements in mechanical properties, with a notable 22.78% enhancement in tensile strength, a significant 35.21% increase in hardness, a noteworthy 24.44% improvement in fatigue strength, and a substantial 28.68% increase in wear resistance observed in aluminum-La2O3 composites produced via FSP. These results underscore the potential of leveraging FSP for aluminum-based composite manufacturing, offering opportunities for the development of high-performance materials with enhanced mechanical properties and durability.

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Section: Primary Reinforcement Particlementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Advancements in Aluminum-Based Composite Manufacturing: Leveraging La2O3 Reinforcement through Friction Stir Process

Kareem,

Raju,

et al. 2024

E3S Web of Conf.

View full text Add to dashboard Cite

show abstract

“…Other researchers preferred firstly to design the model using CAD software, representing it with filaments instead of as a solid part, and then print the scaffold [ 10 , 14 , 18 , 19 , 20 , 21 , 22 , 23 ]. In those cases, they were able to simulate the model behaviour and compare the results with the experimental ones or optimise the part before printing it.…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, there are several valid options to simulate the mechanical performance of the printed scaffold based on its model, such as the homogenisation [24][25][26][27], the voxel-based [12,28,29], or the CAD-based modelling techniques [10,14,[18][19][20][21][22][23]30,31].…”

Section: Introductionmentioning

confidence: 99%

Comparison of CAD and Voxel-Based Modelling Methodologies for the Mechanical Simulation of Extrusion-Based 3D Printed Scaffolds

et al. 2021

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Porous structures are of great importance in tissue engineering. Most scaffolds are 3D printed, but there is no single methodology to model these printed parts and to apply finite element analysis to estimate their mechanical behaviour. In this work, voxel-based and geometry-based modelling methodologies are defined and compared in terms of computational efficiency, dimensional accuracy, and mechanical behaviour prediction of printed parts. After comparing the volumes and dimensions of the models with the theoretical and experimental ones, they are more similar to the theoretical values because they do not take into account dimensional variations due to the printing temperature. This also affects the prediction of the mechanical behaviour, which is not accurate compared to reality, but it makes it possible to determine which geometry is stiffer. In terms of comparison of modelling methodologies, based on process efficiency, geometry-based modelling performs better for simple or larger parts, while voxel-based modelling is more advantageous for small and complex geometries.

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“…In addition to structural analysis, a number of computational methods have been applied to simulate and predict mechanical performance, permeability and tissue formation in 3D printed tissue engineered devices. 1,4,8,16,23,26 Additionally, computational mechanical tests can contribute to the design verification phase of the patient specific device design control development process. 15 Predicting the mechanical performance of a design is dependent on intrinsic properties of materials used in the manufacturing process as well as the specific manufacturing process.…”

Section: Introductionmentioning

confidence: 99%

Evaluating Directional Dependency of Selective Laser Sintered Patient Specific Biodegradable Devices to Improve Predictive Modeling and Design Verification

et al. 2021

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Additive manufacturing, or 3D printing, of the bioresorbable polymer e-polycaprolactone (PCL) is an emerging tissue engineering solution addressing patient specific anatomies. Predictively modeling the mechanical behavior of 3D printed parts comprised of PCL improves the ability to develop patient specific devices that meet design requirements while reducing the testing of extraneous design variants and development time for emergency devices. Predicting mechanical behavior of 3D-printed devices is limited by the variability of effective material moduli that are determined in part by the 3D printing manufacturing process. Powder fusion methods, specifically laser sintering, are known to produce parts with internal porosity ultimately impacting the mechanical performance of printed devices. This study investigates the role of print direction and part size on the material and structural properties of laser sintered PCL parts. Solid PCL cylinders were printed in the XY (perpendicular to laser) and Z direction (parallel to laser), scanned using microcomputed tomography, and mechanically tested under compression. Compositional, structural, and functional properties of the printed parts were evaluated with differential scanning calorimetry, gel permeation chromatography, microcomputed tomography, and mechanical

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Modelling and simulation for fabrication of 3D printed polymeric porous tissue scaffolds

Cited by 21 publications

References 15 publications

Advancements in Aluminum-Based Composite Manufacturing: Leveraging La2O3 Reinforcement through Friction Stir Process

Advancements in Aluminum-Based Composite Manufacturing: Leveraging La2O3 Reinforcement through Friction Stir Process

Comparison of CAD and Voxel-Based Modelling Methodologies for the Mechanical Simulation of Extrusion-Based 3D Printed Scaffolds

Evaluating Directional Dependency of Selective Laser Sintered Patient Specific Biodegradable Devices to Improve Predictive Modeling and Design Verification

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