Modeling the pathways linking childhood hyperactivity and substance use disorder in young adulthood.

Tarter, Ralph E.; Kirisci, Levent; Feske, Ulrike; Vanyukov, Michael

doi:10.1037/0893-164x.21.2.266

Cited by 57 publications

(38 citation statements)

References 42 publications

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“…Findings on internalizing symptomatology (depressive or anxiety-disorder related) are less consistent (for reviews see Cheetham et al, 2010; Colder et al, 2010). Though some studies have shown positive relations of internalizing symptomatology to substance use, results may vary by substance (King et al, 2004; Maskowsky et al, 2014; Tarter et al, 2007) and extent of comorbidity (Colder et al, 2013; Goodman, 2010; King and Chassin, 2007; Pardini et al, 2007; Roberts et al, 2007; Scalco et al, 2014; Schuckit and Smith, 2006; Wittchen et al, 2007). …”

Section: Introductionmentioning

confidence: 99%

Emotional self-control and dysregulation: A dual-process analysis of pathways to externalizing/internalizing symptomatology and positive well-being in younger adolescents

Wills

Simons

Sussman

et al. 2016

Drug and Alcohol Dependence

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Objectives There is little knowledge about how emotional regulation contributes to vulnerability versus resilience to substance use disorder. With younger adolescents, we studied the pathways through which emotion regulation attributes are related to predisposing factors for disorder. Methods A sample of 3,561 adolescents (M age 12.5 years) was surveyed. Measures for emotional self-control (regulation of sadness and anger), emotional dysregulation (angerability, affective lability, and rumination about sadness or anger), and behavioral self-control (planfulness and problem solving) were obtained. A structural model was analyzed with regulation attributes related to six intermediate variables that are established risk or protective factors for adolescent substance use (e.g., academic involvement, stressful life events). Criterion variables were externalizing and internalizing symptomatology and positive well-being. Results Indirect pathways were found from emotional regulation to symptomatology through academic competence, stressful events, and deviance-prone attitudes and cognitions. Direct effects were also found: from emotional dysregulation to externalizing and internalizing symptomatology; emotional self-control to well-being; and behavioral self-control (inverse) to externalizing symptomatology. Emotional self-control and emotional dysregulation had independent effects and different types of pathways. Conclusions Adolescents scoring high on emotional dysregulation are at risk for substance dependence because of more externalizing and internalizing symptomatology. Independently, youth with better behavioral and emotional self-control are at lower risk. This occurs partly through relations of regulation constructs to environmental variables that affect levels of symptomatology (e.g., stressful events, poor academic performance). Effects of emotion regulation were found at an early age, before the typical onset of substance disorder.

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Section: Introductionmentioning

confidence: 99%

Emotional self-control and dysregulation: A dual-process analysis of pathways to externalizing/internalizing symptomatology and positive well-being in younger adolescents

Wills

Simons

Sussman

et al. 2016

Drug and Alcohol Dependence

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“…The symptoms of ADHD (inattention, impulsivity, and hyperactivity) are prominently featured in alcoholism theory as part of the larger construct of behavioral disinhibition integral to alcoholism risk (Iacono, Malone, & McGue, 2008; Pelham & Lang, 1993; Sher, Grekin, & Williams, 2005; Zucker, 2006; Tarter, Kirisci, Feske, & Vanyukov, 2007). Traits such as “impulsive,” “restless,” “hyper,” and “distractible” are thought to reflect a broad behavioral phenotype indicative of inherited family-level risk for alcoholism.…”

Section: Introductionmentioning

confidence: 99%

Childhood attention-deficit/hyperactivity disorder (ADHD) and growth in adolescent alcohol use: The roles of functional impairments, ADHD symptom persistence, and parental knowledge.

Molina¹,

Pelham²,

Cheong³

et al. 2012

Journal of Abnormal Psychology

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Research on the relation between childhood Attention-Deficit/Hyperactivity Disorder (ADHD) and adolescent alcohol use has found mixed results. Studies are needed that operationalize alcohol use in developmentally appropriate ways and that test theoretically plausible moderators and mediators in a longitudinal framework. The current study tested childhood ADHD as a predictor of alcohol use frequency at age 17, and age-related increases in alcohol use frequency, through adolescence for 163 adolescents with ADHD diagnosed in childhood and 120 adolescents without ADHD histories. Childhood ADHD did not predict either alcohol outcome. However, parental knowledge of the teen’s friendships, activities, and whereabouts moderated the association such that childhood ADHD predicted alcohol use frequency at age 17 when parental knowledge was below median levels for the sample. Mediational pathways that explained this risk included social impairment, persistence of ADHD symptoms, grade point average, and delinquency. Social impairment was positively associated with alcohol use frequency through delinquency; it was negatively associated with alcohol use frequency as a direct effect independent of delinquency. These nuanced moderated-mediation findings help to explain previously inconsistent results for the ADHD-adolescent alcohol use association. The findings also imply that future research and intervention efforts should focus on ADHD-related social and academic impairments as well as symptom persistence and parenting efforts.

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“…The overall sample size and high threshold for CD diagnosed in the original study warrant focus in a larger, future investigation. Prior study findings focusing on the predictive role of CD could not be replicated given the high threshold for making the CD diagnosis using the WASH-U-K-SADS in the current sample; prior studies reviewed suggest conduct problems mediate the relationship between hyperactivity and SUD (Tarter, Kirisci, Feske, & Vanyukov, 2007); the comorbidity of CD with ADHD predicts or worsens risk for SUD (Molina & Pelham, 2003; Molina, Smith, & Pelham, 1999) and criminality (Moffitt, 1990); and that, after controlling for CD, ADHD no longer predicts SUD (Brook et al, 2010; Lynskey & Hall, 2001). However, Wilens et al (2011) found ADHD to predict SUD even after controlling for CD, which in our sample was unnecessary.…”

Section: Discussionmentioning

confidence: 87%

Parental warmth and risks of substance use in children with attention-deficit/hyperactivity disorder

Tandon

Tillman

Spitznagel

et al. 2013

Addiction Research & Theory

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Objective The study examined factors in the risk trajectory for Substance Use Disorder (SUD) over a 10–12 year period in children with ADHD. Method N=145 children between the ages of 7 and 16 with ADHD and healthy controls were assessed every 2 years for 10–12 years as part of a larger, longitudinal investigation. Onset of substance use disorder was examined using Cox proportional hazards modeling, and included child and parent psychopathology, and parental warmth as well as other key factors. Results Low paternal warmth and maternal SUD were predictors of SUD in n=59 ADHD participants after adjusting for gender, child ODD, paternal SUD, maternal/paternal ADHD, maternal/paternal major depressive disorder (MDD), maternal/paternal anxiety, and low maternal warmth in the Cox model. Conclusions Longitudinal study findings suggest that in addition to the established risk of ADHD and maternal SUD in development of child SUD, low paternal warmth is also associated with onset of SUD. This was evident after controlling for pertinent parent and child psychopathology. These findings suggest that paternal warmth warrants further investigation as a key target for novel interventions to prevent SUD in children with ADHD. More focused investigations examining paternal parenting factors in addition to parent and child psychopathology in the risk trajectory from ADHD to SUD are now warranted.

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Modeling the pathways linking childhood hyperactivity and substance use disorder in young adulthood.

Cited by 57 publications

References 42 publications

Emotional self-control and dysregulation: A dual-process analysis of pathways to externalizing/internalizing symptomatology and positive well-being in younger adolescents

Emotional self-control and dysregulation: A dual-process analysis of pathways to externalizing/internalizing symptomatology and positive well-being in younger adolescents

Childhood attention-deficit/hyperactivity disorder (ADHD) and growth in adolescent alcohol use: The roles of functional impairments, ADHD symptom persistence, and parental knowledge.

Parental warmth and risks of substance use in children with attention-deficit/hyperactivity disorder

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