Modeling the evolution of segment trees reveals deficiencies in current inferential methods for genomic reassortment
Qianying Lin,
Emma E. Goldberg,
Thomas Leitner
et al.
Abstract:Reassortment is an evolutionary process common in viruses with segmented genomes. These viruses can swap whole genomic segments during cellular co-infection, giving rise to new viral variants. Large-scale genome rearrangements, such as reassortment, have the potential to quickly generate new phenotypes, making the understanding of viral reassortment important to both evolutionary biology and public health research. In this paper, we argue that reassortment cannot be reliably inferred from incongruities between… Show more
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