Modeling statistical metadata

Papageorgiou, H.; Pentaris, Fragkiskos; Theodorou, E.; Vardaki, Maria; Petrakos, M.

doi:10.1109/ssdm.2001.938535

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…The analysis can be linked to individual spot records, or spots matched between gels. A formal description of statistical analysis presented by Papageorgiou et al (2001) covers most of the attributes that are applicable to proteomics analysis, but is possibly too complex for use in biological applications. Our model has few attributes, with the intention that the details of the analysis will be described with data types obtained from controlled vocabularies.…”

Section: Discussionmentioning

confidence: 99%

Proposal for a standard representation of two‐dimensional gel electrophoresis data

2003

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The global analysis of proteins is now feasible due to improvements in techniques such as two-dimensional gel electrophoresis (2-DE), mass spectrometry, yeast two-hybrid systems and the development of bioinformatics applications. The experiments form the basis of proteomics, and present significant challenges in data analysis, storage and querying. We argue that a standard format for proteome data is required to enable the storage, exchange and subsequent re-analysis of large datasets. We describe the criteria that must be met for the development of a standard for proteomics. We have developed a model to represent data from 2-DE experiments, including difference gel electrophoresis along with image analysis and statistical analysis across multiple gels. This part of proteomics analysis is not represented in current proposals for proteomics standards. We are working with the Proteomics Standards Initiative to develop a model encompassing biological sample origin, experimental protocols, a number of separation techniques and mass spectrometry. The standard format will facilitate the development of central repositories of data, enabling results to be verified or re-analysed, and the correlation of results produced by different research groups using a variety of laboratory techniques.

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Section: Discussionmentioning

confidence: 99%

Proposal for a standard representation of two‐dimensional gel electrophoresis data

2003

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“…As we have already pointed out in [11], there are known attempts concerning the modelling and use of statistical data on the Web of Data [4,10,24,25]. However, unlike earlier attempts such as [16,19], we aim at a light-weight solution enabling a quick uptake and wide deployment.…”

Section: Related Workmentioning

confidence: 99%

SCOVO: Using Statistics on the Web of Data

Hausenblas

Halb

Raimond³

et al. 2009

Lecture Notes in Computer Science

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Statistical data is present everywhere-from governmental bodies to economics, from life-science to industry. With the rise of the Web of Data, the need for sharing, accessing, and using this data has entered a new stage. In order to enable proprietary, closed-world formats, to enter the Web of Data, we propose a framework for modelling and publishing statistical data. To illustrate the usefulness of our approach we demonstrate its application in real-world statistical datasets.

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An integrated metadata model for statistical data collection and processing

Vardaki¹,

Papageorgiou²

Proceedings. 16th International Conference on Scientific and Statistical Database Management, 2004.

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Modeling statistical metadata

Cited by 3 publications

References 13 publications

Proposal for a standard representation of two‐dimensional gel electrophoresis data

Proposal for a standard representation of two‐dimensional gel electrophoresis data

SCOVO: Using Statistics on the Web of Data

An integrated metadata model for statistical data collection and processing

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