Modeling Serpin Conformational Diseases in Drosophila melanogaster

Jahn, Thomas R.; Malzer, Elke; Roote, John; Vishnivetskaya, Anastasia; Imarisio, Sara; Giannakou, Maria E.; Panser, Karin; Marciniak, Stefan J.; Crowther, Damian C.

doi:10.1016/b978-0-12-386471-0.00012-2

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Dipeptidyl-peptidase III (Dppiii) Cleaves the N-terminal Dip...1

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2021

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“…Along with these different proteases, two major classes of secreted inhibitors have been discovered, serine proteases inhibitors (SERPIN) and endopeptidase inhibitors. The D. melanogaster genome contains 29 serpin genes (195)(196)(197) and four of these gene products were identified: Spn38F (Serpin 3), Spn43Ab, Spn55B (Serpin 6) and Spn88Ea (Serpin 5).…”

Section: Dipeptidyl-peptidase III (Dppiii) Cleaves the N-terminal Dip...mentioning

confidence: 99%