Abstract:Reactive species (RS) are known to play significant roles in cancer development as well as in treating or managing cancer. On the other hand, genome scale metabolic models are being used to understand cell metabolism in disease contexts including cancer, and also in planning strategies to handle diseases. Despite their crucial roles in cancers, the reactive species have not been adequately modeled in the genome scale metabolic models (GSMMs) when probing disease models for their metabolism or detection of drug… Show more
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