Modeling peristaltic flow in vessels equipped with valves: Implications for vasomotion in bat wing venules

Farína, Angiolo; Fusi, Lorenzo; Fasano, Antonio; Ceretani, Andrea N.; Rosso, Fábio

doi:10.1016/j.ijengsci.2016.07.002

Cited by 25 publications

(32 citation statements)

References 24 publications

(37 reference statements)

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“…An important unsteady propagation mechanisms for transport is peristalsis which is a radially symmetrical contraction and relaxation of muscles that propagates materials in a wave-like motion along a conduit utilizing deformable walls. This mechanism arises in an astonishing range of biological systems including pharyngeal physiology [22], vasomotion (periodic oscillations of blood vessels walls) in bat wing venules [23], pulmonary and perivascular space (PVS) dynamics [24], bile migration in the gastric tract [25]. Peristalsis has also been implemented in several bio-inspired medical devices including nano-scale pharmacological delivery systems [26,27], fish locomotion for underwater robots [28] and biomimetic worm soft peristaltic land crawling robots [29,30].…”

Section: Introductionmentioning

confidence: 99%

Analytical Study of Electro-Osmosis Modulated Capillary Peristaltic Hemodynamics

Tripathi

Bhushan

Bég

2017

J. Mech. Med. Biol.

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A mathematical model is developed to analyze electro-kinetic effects on unsteady peristaltic transport of blood in cylindrical vessels of finite length. The Newtonian viscous model is adopted. The analysis is restricted under Debye–Hückel linearization (i.e., wall zeta potential [Formula: see text] 25[Formula: see text]mV) is sufficiently small). The transformed, nondimensional conservation equations are derived via lubrication theory and long wavelength and the resulting linearized boundary value problem is solved exactly. The case of a thin electric double layer (i.e., where only slip electro-osmotic velocity considered) is retrieved as a particular case of the present model. The response in pumping characteristics (axial velocity, pressure gradient or difference, volumetric flow rate, local wall shear stress) to the influence of electro-osmotic effect (inverse Debye length) and Helmholtz–Smoluchowski velocity is elaborated in detail. Visualization of trapping phenomenon is also included and the bolus dynamics evolution with electro-kinetic effects examined. A comparative study of train wave propagation and single wave propagation is presented under the effects of thickness of EDL and external electric field. The study is relevant to electrophoresis in haemotology, electrohydrodynamic therapy and biomimetic electro-osmotic pumps.

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Section: Introductionmentioning

confidence: 99%

Analytical Study of Electro-Osmosis Modulated Capillary Peristaltic Hemodynamics

Tripathi

Bhushan

Bég

2017

J. Mech. Med. Biol.

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“…Peristaltic pumping is also a significant biological mechanism arises in a spectacular range of biological phenomenons including pharyngeal physiology [30] pulmonary, perivascular space dynamics [31], and periodic vibration of blood vessels walls (vasomotion) in bat wing venule [32]. It arises in several diverse systems in human cytology and nature like embryological transport, gastrointestinal motion, plant translocation, and snake and earthworm locomotion.…”

Section: Abbreviations: Edl Electric Double Layermentioning

confidence: 99%

Microvascular blood flow with heat transfer in a wavy channel having electroosmotic effects

et al. 2020

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The present paper addresses microvascular blood flow with heat and mass transfer in complex wavy microchannel modulated by electroosmosis. Investigation is carried out with joule heating and chemical reaction effects. Further, viscous dissipation is also considered. Using Debye-Huckel, lubrication theory, and long wavelength approximations, analytical solutions of dimensionless boundary value problems are obtained. The impacts of different parameters are examined for temperature and concentration profile. Furthermore, nature of pressure rise is also investigated to analyze the pumping characteristics. Important results of flow phenomena are explored by means of graphs.

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“…Thus, the peristaltic action results in pressure pulses greatly enhancing the effect of the heart generated hydraulic pressure gradient. As a consequence the vessel resistance is considerably reduced, as shown in Farina et al 4 Indeed, by preventing reflux, microvalves turn the periodic oscillations of venules walls into a pumping action. In the contraction phase the rear valve closes, while expansion causes the closure of the front valve, thus making flow unidirectional.…”

Section: Introductionmentioning

confidence: 95%

“…In particular, the authors claimed that the arterioles hydraulic resistance increases as the amplitude of vasomotion increases and this result appears consistent with experimental observations. The whole matter of blood dynamics in the presence of vasomotion has been recently reconsidered in Farina et al 4 and Fasano et al, 5 where the authors made a clear distinction between the flow in the venules and in arterioles. In a recent paper Dongaonkar et al 6 experimenting on batwings focused on the presence of valves in venules.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Blood flow in venules: A mathematical model including valves inertia

Cardini

Farína

Fasano

et al. 2019

Veins and Lymphatics

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It is well known that venules equipped with valves play a critical role in regulating blood flow. Essentially they are peristaltic pumps that increase the efficiency of venous blood return to the heart, thanks to the presence of valves preventing backflow. Inspired by two recent papers, we have modeled the venule as a vessel with valves placed at its ends and walls animated by radial oscillations that are independent of heart pulsation and respiratory rhythm. Differently from the previous papers, the present model takes into account the valves inertia allowing, for progressive closing/opening stages. The numerical simulations produce a pressure pulse and a velocity profile which agree almost perfectly with the experimental data of Dongaonkar et al., eliminating the discrepancies found in Farina et al., arising from the hypothesis that valves act instantaneously.

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Modeling peristaltic flow in vessels equipped with valves: Implications for vasomotion in bat wing venules

Cited by 25 publications

References 24 publications

Analytical Study of Electro-Osmosis Modulated Capillary Peristaltic Hemodynamics

Analytical Study of Electro-Osmosis Modulated Capillary Peristaltic Hemodynamics

Microvascular blood flow with heat transfer in a wavy channel having electroosmotic effects

Blood flow in venules: A mathematical model including valves inertia

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