Modeling of Multiple Equilibria in the Self-Aggregation of Di-n-decyldimethylammonium Chloride/Octaethylene Glycol Monododecyl Ether/Cyclodextrin Ternary Systems

Abstract

The surface tension equations of binary surfactant mixtures (di-n-decyldimethylammonium chloride and octaethylene glycol monododecyl ether) are established by combining the Szyszkowski equation of surfactant solutions, the ideal or nonideal mixing theory, and the phase separation model. For surfactant mixtures, the surface tension at the air-water interface is calculated using nonideal theory due to synergism between the two adsorbed surfactant types. The incorporation of cyclodextrin complexation model to the surface tension equations gives a robust model for the description of the surface tension isotherms of binary, ternary, and more complex systems involving numerous inclusion complexes. The surface tension data obtained experimentally shows excellent agreement with the theoretical model below and above the formation of micelles. The strong synergistic effect observed between the two surfactants is disrupted by the presence of CDs, leading to ideal behavior of ternary systems. Indeed, depending on the nature of the cyclodextrin (i.e., α, β, or γ), which allows a tuning of the cavity size, the binding constants with the surfactants are modified as well as the surface properties due to strong modification of equilibria involved in the ternary mixture.

How to improve the chemical disinfection of contaminated surfaces by viruses, bacteria and fungus?

“… c Determined from surface tension modelling using single surfactant/cyclodextrin systems in aqueous solution with dilution experiments. d Taken in Leclercq et al., 2013 . …”

Displacement of Drugs From Cyclodextrin Complexes by Bile Salts: A Suggestion of an Intestinal Drug-Solubilizing Capacity From an In Vitro Model

“…For the technical details of combining these with the constitutive equation, the reader is referred to the literature. [40][41][42]…”

Physicochemical Properties and Phase Behavior of Didecyldimethylammonium Chloride/Alkyl Polyglycoside Surfactant Mixtures

“…Previous work has indicated that double-tailed cationic surfactants have been widely used as fabric softeners, antimicrobials, and antistatic agents [20] in many formulations because of their strong absorbability onto negative surfaces. APG and didecyldimethylammonium chloride (DDAC) mixtures, combining the advantages of pure APG and DDAC, are of particular interest and importance in the development of multi-functional disinfection and washing products [21][22][23][24].…”