A technique was developed for fabricating spherical shell targets for implosion physics experiments with diameters up to several millimeters and with unique structural features such as thin metal layers or texture on the inside surface. We start with a spherical bead or thin shell of poly͑alpha-methylstyrene͒ ͑PAMS͒ of the desired size, which can be textured by laser photoablation or overcoated with a thin layer of diagnostic material. The mandrel is next overcoated with plasma polymer ͑CH͒ 2-50 m thick. Upon heating, the PAMS depolymerizes to a gaseous monomer which diffuses through the thermally stable plasma polymer coating leaving a hollow shell. Shells produced by this technique are uniform in wall thickness, and highly spherical. If the PAMS mandrel is textured, the mandrel topology is transferred to the inner wall of the plasma polymer shell. Likewise, thermally stable coatings on the mandrel are transferred to the inner shell wall.