Modeling of interaction between therapeutic ultrasound propagation and cavitation bubbles

Liebler, Marko; Dreyer, Thomas; Riedlinger, Rainer

doi:10.1016/j.ultras.2006.07.006

Cited by 13 publications

(17 citation statements)

References 7 publications

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“…This may be due to the effect of tensile wave shortening from the cavitation that is produced by the tensile portion. [32][33][34][35] Since the computation does not include cavitation, this effect is not modeled and the numerical result contains the full non-attenuated tensile portion. Figure 7 shows that the distribution of peak pressures in the focal plane for 13.8 and 15.8 kV input is well captured by the model except for an approximate 10% difference in P þ near the focus.…”

Section: A Validation Using Original Lensmentioning

confidence: 99%

Experimentally validated multiphysics computational model of focusing and shock wave formation in an electromagnetic lithotripter

Fovargue

Mitran

Smith

et al. 2013

The Journal of the Acoustical Society of America

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A multiphysics computational model of the focusing of an acoustic pulse and subsequent shock wave formation that occurs during extracorporeal shock wave lithotripsy is presented. In the electromagnetic lithotripter modeled in this work the focusing is achieved via a polystyrene acoustic lens. The transition of the acoustic pulse through the solid lens is modeled by the linear elasticity equations and the subsequent shock wave formation in water is modeled by the Euler equations with a Tait equation of state. Both sets of equations are solved simultaneously in subsets of a single computational domain within the BEARCLAW framework which uses a finite-volume Riemann solver approach. This model is first validated against experimental measurements with a standard (or original) lens design. The model is then used to successfully predict the effects of a lens modification in the form of an annular ring cut. A second model which includes a kidney stone simulant in the domain is also presented. Within the stone the linear elasticity equations incorporate a simple damage model.

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Section: A Validation Using Original Lensmentioning

confidence: 99%

Experimentally validated multiphysics computational model of focusing and shock wave formation in an electromagnetic lithotripter

Fovargue

Mitran

Smith

et al. 2013

The Journal of the Acoustical Society of America

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“…30 to 3 · 10 5 per ml).The work has been stimulated by the findings that the life-time of cavitation bubbles increases with higher bubble densities [11][12][13] . The analysis presented in this paper might be relevant to the field of shock wave lithotripsy where recent numerical works 11,15 emphasize the effect of nuclei concentration on the cluster dynamics.…”

Section: Introductionmentioning

confidence: 96%

Effect of nuclei concentration on cavitation cluster dynamics

Arora

Ohl

Lohse

2007

The Journal of the Acoustical Society of America

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Cavitation cluster dynamics after the passage of a single pressure wave is studied for different concentrations of artificial cavitation nuclei (30 to 3 · 10 5 nuclei/ml). With increasing concentration of cavitation nuclei the life time of the cavitation cluster is prolonged. Additionally, we find that the spatial extent of the cluster decreases with higher nuclei concentration. The experimental data for concentrations less than 400 nuclei/ml are compared to simulations with a Rayleigh-Plesset type equation, taking into account bubble-bubble interaction. For higher concentrations (more than 1000 nuclei/ml) the observed radial cluster dynamics is compared with an calculations from axisymmetric cavitycollapse model.2

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“…Clinical experience has demonstrated that the treatment outcome of SWL depends critically on the design features and operating conditions of a lithotripter, with much emphasis given to the pulserepetition frequency (PRF) [3][4][5][6][7]. Even a slight increase in the PRF from 1 to 2 Hz is shown to significantly decrease the effectiveness of treatment [8].…”

Section: Introductionmentioning

confidence: 99%

“…When bubble proliferation occurs in the beam path, the tensile component of the lithotripter pulse is attenuated due to loss of the tensile wave energy to expanding cavitation bubbles [1,5,9]. This tensile attenuation has been shown to depend on the density of cavitation nuclei in the beam path and is sensitive to the PRF [17].…”

Section: Introductionmentioning

confidence: 99%

Bubble Proliferation or Dissolution of Cavitation Nuclei in the Beam Path of a Shock-Wave Lithotripter

et al. 2015

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It is hypothesized that the decreased treatment efficiency in contemporary shock-wave lithotripters is related to tensile wave attenuation due to cavitation in the prefocal beam path. Utilizing high-speed imaging of the beam path and focal pressure waveform measurements, tensile attenuation is associated with bubble proliferation. By systematically testing different combinations of pulse-repetition frequency and gas concentration, we modulate the bubble-dissolution time to identify which conditions lead to bubble proliferation and show that reducing bubble proliferation in the beam path significantly improves acoustic transmission and stone comminution efficiency in vitro. In addition to experiments, a bubbleproliferation model is developed that takes gas diffusion across the bubble wall and bubble fragmentation into account. By aligning the model with experimental observations, the number of daughter bubbles produced after a single lithotripter bubble collapse is estimated to be in the range of 253 ∼ 510. This finding is on the same order of magnitude with previous measurements of an isolated bubble collapse in a lithotripter field by Williams [BJU Int. 102, 1681 (2008)], and this estimate improves the general understanding of lithotripsy bubble dynamics in the beam path.

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Modeling of interaction between therapeutic ultrasound propagation and cavitation bubbles

Cited by 13 publications

References 7 publications

Experimentally validated multiphysics computational model of focusing and shock wave formation in an electromagnetic lithotripter

Experimentally validated multiphysics computational model of focusing and shock wave formation in an electromagnetic lithotripter

Effect of nuclei concentration on cavitation cluster dynamics

Bubble Proliferation or Dissolution of Cavitation Nuclei in the Beam Path of a Shock-Wave Lithotripter

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