Modeling Nasal Physiology Changes due to Septal Perforations

Cannon, Daniel E.; Frank, Dennis O.; Kimbell, Julia S.; Poetker, David M.; Rhee, John S.

doi:10.1177/0194599812451438a38

Cited by 20 publications

(42 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mechanisms causing the symptoms of nasal septal perforation have not been fully elucidated. Some reports have shown that septal perforation causes abnormal airflow using a computer simulation of the airway [3][4][5][6] but it should be noted that all these simulations were performed using an artificial perforation. In the current study, we analyzed the effects of nasal septum perforation repair on three-dimensional airflow using perforation model reconstructed based on computed tomography (CT) data of a patient, and tried to determine the causes of nasal perforation symptoms and to predict the post-operative nasal function.…”

Section: Introductionmentioning

confidence: 99%

Effects of nasal septum perforation repair surgery on three-dimensional airflow: an evaluation using computational fluid dynamics

Nomura

Ushio

Kondo

et al. 2014

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

The purpose of this research is to determine the cause of nasal perforation symptoms and to predict post-operative function after nasal perforation repair surgery. A realistic three-dimensional (3D) model of the nose with a septal perforation was reconstructed using a computed tomography (CT) scan from a patient with nasal septal defect. The numerical simulation was carried out using ANSYS CFX V13.0. Pre- and post-operative models were compared by their velocity, pressure gradient (PG), wall shear (WS), shear strain rate (SSR) and turbulence kinetic energy in three plains. In the post-operative state, the crossflows had disappeared, and stream lines bound to the olfactory cleft area had appeared. After surgery, almost all of high-shear stress areas were disappeared comparing pre-operative model. In conclusion, the effects of surgery to correct nasal septal perforation were evaluated using a three-dimensional airflow evaluation. Following the surgery, crossflows disappeared, and WS, PG and SSR rate were decreased. A high WS.PG and SSR were suspected as causes of nasal perforation symptoms.

show abstract

Section: Introductionmentioning

confidence: 99%

Effects of nasal septum perforation repair surgery on three-dimensional airflow: an evaluation using computational fluid dynamics

Nomura

Ushio

Kondo

et al. 2014

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

show abstract

“…Mathematical models have been used extensively to analyze nasal airflow patterns in a number of postsurgical conditions , . These CFD studies have demonstrated a close relation between numerical simulations and in‐vivo measurements of nasal air conditioning .…”

Section: Discussionmentioning

confidence: 99%

“…A laminar airflow is assumed in the majority of studies, which has support in experimental studies of healthy nasal cavities . Other CFD investigations of nasal physiology have used steady‐state or turbulent models to simulate nasal airflow . However, there are no data on the flow patterns in nasal cavities after extensive surgical resection.…”

Section: Discussionmentioning

confidence: 99%

“…Numerical simulations of airflow have been shown to approximate in‐vivo conditions and provide objective data about flow patterns, as well as heat and water transfer . CFD has been utilized to evaluate surgical outcomes and to enhance the understanding of disease states, including nasal airway obstruction, septal perforation, and ENS . However, no CFD studies have investigated the effects of CFR on nasal airflow patterns and conditioning.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Impact of endoscopic craniofacial resection on simulated nasal airflow and heat transport

Tracy

Basu

Shah

et al. 2019

Int Forum Allergy Rhinol

Self Cite

View full text Add to dashboard Cite

Background: Endoscopic craniofacial resections (CFR) are performed for extensive anterior skull base lesions. This surgery involves removal of multiple intranasal structures, potentially leading to empty nose syndrome (ENS). However, many patients remain asymptomatic postoperatively. Our objective was to analyze the impact of CFR on nasal physiology and airflow using computational fluid dynamics (CFD). This is the first CFD analysis of post-CFR patients.Methods: Three-dimensional sinonasal models were constructed from 3 postoperative images using Mimics TM . Hybrid computational meshes were created. Steady inspiratory airflow and heat transport were simulated at patientspecific flow rates using shear stress transport k-omega turbulent flow modeling in Fluent TM . Simulated average heat flux (HF) and surface area where HF exceeded 50 W/m 2 (SAHF50) were compared with laminar simulations in 9 radiographically normal adults.Results: Three adults underwent CFR without developing ENS. Average HF (W/m 2 ) were 132.70, 134.84, and 142.60 in the CFR group, ranging from 156.24 to 234.95 in the nonoperative cohort. SAHF50 (m 2 ) values were 0.0087, 0.0120, and 0.0110 in the CFR group, ranging from 0.0082 to 0.0114 in the radiographically normal cohort. SAHF50 was distributed throughout the CFR cavities, with increased HF at the roof and walls compared with the nonoperative cohort. Conclusion:Average HF was low in the CFR group compared with the nonoperative group. However, absence of ENS in most CFR patients may be due to large stimulated mucosal surface area, commensurate with the nonoperative cohort. Diffuse distribution of stimulated area may result from turbulent mixing a er CFR. To be er understand heat transport post-CFR, a larger cohort is necessary. C 2019 ARS-AAOA, LLC.

show abstract

“…The complexity of LTS airway obstruction, coupled with the variable nature of LTS, can be better understood using contemporary computational tools to aid clinicians in the diagnosis and treatment of this condition. Computational fluid dynamics (CFD) modeling have shown significant promise in analyzing airflow profile and particle transport in the sinonasal cavity, [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] as well as characterizing laryngeal flow circulation. [37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54] However, CFD techniques have not been fully utilized in evaluating LTS-induced airway obstruction.…”

Section: Introductionmentioning

confidence: 99%

Investigating the effects of laryngotracheal stenosis on upper airway aerodynamics

et al. 2017

View full text Add to dashboard Cite

show abstract

Modeling Nasal Physiology Changes due to Septal Perforations

Cited by 20 publications

References 0 publications

Effects of nasal septum perforation repair surgery on three-dimensional airflow: an evaluation using computational fluid dynamics

Effects of nasal septum perforation repair surgery on three-dimensional airflow: an evaluation using computational fluid dynamics

Impact of endoscopic craniofacial resection on simulated nasal airflow and heat transport

Investigating the effects of laryngotracheal stenosis on upper airway aerodynamics

Contact Info

Product

Resources

About