Modeling and simulation of vascular tumors embedded in evolving capillary networks
Marvin Fritz,
Prashant K. Jha,
Tobias Köppl
et al.
Abstract:In this work, we present a coupled 3D-1D model of tumor growth within a dynamically changing vascular network to facilitate realistic simulations of angiogenesis. Additionally, the model includes ECM erosion, interstitial flow, and coupled flow in vessels and tissue. We employ continuum mixture theory with stochastic Cahn-Hilliard type phase-field models of tumor growth. The interstitial flow is governed by a mesoscale version of Darcy's law. The flow in the blood vessels is controlled by Poiseuille flow, and … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.