Abstract:Deep Brain Stimulation (DBS) is effective in the Parkinsonian state, while it seems to produce rather non-selective stimulation over an unknown volume of tissue. Despite a huge amount of anatomical and physiological data regarding the structure of the basal ganglia (BG) and their connections, the computational processes performed by the basal ganglia in health and disease still remain unclear. Its hypothesized roles are discussed in this chapter as well as the changes that are observed under pathophysiological… Show more
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