Modeling and Prediction of the Immediate and Short-Term Effect of Myopic Orthokeratology

Sánchez‐García, Alicia; Molina‐Martín, Ainhoa; Ariza-Gracia, Miguel Ángel; Piñero, David P.

doi:10.1097/icl.0000000000000962

Cited by 2 publications

(2 citation statements)

References 32 publications

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“…1 Additionally, the sagittal height showed a significant increase (became less negative) in the temporal area for radii between 2.5 and 3.0 mm. In a recent study, Sanchez-García et al 38 observed a higher increase of epithelial thickness in the nasal midperipheral area than in the temporal region after ortho-k wear. Differences between opposing corneal areas (i.e., nasal vs. temporal) may be induced by slight, but clinically acceptable, decentration of the CL.…”

Section: Discussionmentioning

confidence: 89%

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Orthokeratology effect on the corneoscleral profile: Beyond the bull's eye

Martínez‐Plaza,

López‐de la Rosa,

Molina‐Martín

et al. 2024

Ophthalmic Physiologic Optic

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PurposeTo assess the impact of 3 months of orthokeratology (ortho‐k) contact lenses (CLs) for myopia correction on the corneoscleral profile, as changes in scleral geometry could serve as indirect evidence of alteration in the corneal biomechanical properties.MethodsTwenty subjects (40 eyes) were recruited to wear ortho‐k lenses overnight; however, after discontinuation (two CL fractures, one under‐correction and two non‐serious adverse events), 16 subjects (31 eyes) finished a 3‐month follow‐up. Corneoscleral topographies were acquired using the Eye Surface Profiler (ESP) system before and after 3 months of lens wear. Steep (SimKs) and flat (SimKf) simulated keratometry and scleral sagittal height measurements for 13‐, 14‐ and 15‐mm chord lengths were automatically calculated by the ESP software. Additionally, sagittal height and slope were calculated in polar format from 21 radii (0–10 mm from the corneal apex) at 12 angles (0–330°). Linear mixed models were fitted to determine the differences between visits.ResultsSimKs and SimKf were increased significantly (p ≤ 0.02). The sagittal height in polar format increased significantly (p = 0.046) at a radius of 2.5 mm for 150°, 180°, 210° and 240° orientations and at a radius of 3.0 mm for 210°. Additionally, the slope in polar format significantly decreased (p ≤ 0.04) at radii ranges of 0.0–0.5, 0.5–1.0 and 1.0–1.5 mm for multiple angles and at a radii range of 5.0–5.5 mm for 90°. It also increased significantly (p ≤ 0.045) at a radii range of 1.5–2.0 mm for 30° and at radii ranges of 2.0–2.5, 2.5–3.0 and 3.0–3.5 mm for multiple angles. No significant changes were found for any parameter measured from the scleral area.ConclusionsThree months of overnight ortho‐k lens wear changed the central and mid‐peripheral corneal geometry as expected, maintaining the peripheral cornea and the surrounding sclera stability.

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Section: Discussionmentioning

confidence: 89%

“…Additionally, the sagittal height showed a significant increase (became less negative) in the temporal area for radii between 2.5 and 3.0 mm. In a recent study, Sanchez‐García et al 38 . observed a higher increase of epithelial thickness in the nasal mid‐peripheral area than in the temporal region after ortho‐k wear.…”

Section: Discussionmentioning

confidence: 90%

Orthokeratology effect on the corneoscleral profile: Beyond the bull's eye

Martínez‐Plaza,

López‐de la Rosa,

Molina‐Martín

et al. 2024

Ophthalmic Physiologic Optic

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Analysis of Treatment Discontinuation in Orthokeratology: Studying Efficacy, Safety, and Patient Adherence Over Six Months

Sánchez-García,

Molina-Martin,

Ariza-Gracia

et al. 2024

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

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Purpose: This study aimed to evaluate the efficacy, safety, and participant compliance of orthokeratology treatment for the correction of myopic refractive errors over a six-month prospective study and to define the potential reasons for early treatment discontinuation. Methods: A total of 32 participants with low-to-moderate myopia were fitted with the spherical model of corneal refractive therapy (CRT) orthokeratology lenses (Paragon Vision Sciences) and followed over six months, with specific attention to alterations in refractive error, corneal topography, and epithelial thickness. Concurrently, participant feedback and reasons for any treatment discontinuation were documented. Results: Significant changes in refractive error and in corneal topography were observed, with approximately 50% of the refractive error being corrected on the first night of use and 100% by the first two weeks (P<0.001). Central epithelial thickness experienced substantial thinning, reducing to 15.65±4.49 μm (67.38%) (P<0.001) after 6 months of lens use. Six participants withdrew from this study for varied reasons, including unmet visual expectations and difficulty adhering to the lens-wearing regimen. Notably, the dropout group exhibited higher baseline low-order aberrations and less prolate corneas than those who persisted with the treatment (P<0.05). Conclusion: Orthokeratology with CRT is efficacious and safe for the correction of low-to-moderate myopia in adults, but a portion of patients discontinue the treatment in the first 6 months of contact lens wear. Special care should be taken when recommending orthokeratology in patients with higher levels of myopia and corneas with less prolate shape, providing more realistic expectations and even changing to dual axis or more sophisticated designs.

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Modeling and Prediction of the Immediate and Short-Term Effect of Myopic Orthokeratology

Cited by 2 publications

References 32 publications

Orthokeratology effect on the corneoscleral profile: Beyond the bull's eye

Orthokeratology effect on the corneoscleral profile: Beyond the bull's eye

Analysis of Treatment Discontinuation in Orthokeratology: Studying Efficacy, Safety, and Patient Adherence Over Six Months

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