Modeling and analysis of reverse-fixed piezoelectric tube fiber scanner for two-photon endomicroscopy

Abstract

Miniature two-photon microscopy combines the two-photon excitation principle and is more lightweight and flexible, allowing it to be applied to freely behaving animals. The piezoelectric tube (PZT) fiber scanner is the key actuated component in miniature fiber-scanning two-photon endomicroscopy (TPEM). In this paper, we use multi-physics field finite element simulation to model and analyze a reverse-fixed PZT fiber scanner for TPEM. The simulation results show that the first two resonant frequencies of the PZT fiber scanner are 163.6 Hz and 757.9 Hz, respectively. At the first two resonant points, the PZT fiber scanner scan range are 0.078 mm and 0.68 mm, respectively. Theoretical guidance for frequency selection of the reverse-fixed PZT fiber scanner is provided by these simulation results.

Comparison between forward-fixed and reverse-fixed PZT fiber scanner for nonlinear endomicroscopy

“… of approximately 6.95 μm/V. Contrastingly, the simulated results for the reverse-fixed PZT fiber scanner, employing an identical cantilever length [10], the reverse-fixed PZT fiber scanner exhibits a first-order driving coefficient 1…”

“…In the reverse-fixed scheme, the fiber is positioned inside the PZT component, mitigating limitations stemming from heightened rigidity in probe integration associated with external fiber placement. Our previous studies encompassed analyses and measurements of the theoretical model [10] and scanning characteristics [11] of a reverse-fixed fiber scanner employing PZT (with an outer diameter (OD) of 3.2mm, an inner diameter (ID) of 2.2 mm). However, the utilization of PZT with an OD of 1 mm or less faces challenges when applying the reverse-fixed scheme, primarily constrained by PZT's ID.…”

Modeling and measurement of a miniature piezoelectric ceramic tube fiber scanner for two-photon endomicroscopy

“…performed modal analysis on a piezoelectric bimorph fiber scanner, confirming its suitability for Lissajous, raster, and spiral scanning. Wang et al 28 . investigated the resonant modes and scanning range of a reverse-fixed 3.2-mm-OD PZT fiber scanner designed for TPEM in 2022.…”

“…In 2019, Tekpınar et al 27 performed modal analysis on a piezoelectric bimorph fiber scanner, confirming its suitability for Lissajous, raster, and spiral scanning. Wang et al 28 investigated the resonant modes and scanning range of a reverse-fixed 3.2-mm-OD PZT fiber scanner designed for TPEM in 2022. However, the effects of PZT parameters on the scanning characteristics of this scanner were not discussed.…”