“…We attempted to synthesize 2 by using the Sandmyer reaction from 3,5-dimethoxyaniline with CuBr and HBr, 11) (deacetoxyiodo)benzene-mediated oxidative nuclear halogenation of arene developed by Karade et al,12) and 3,5-dimethoxylation of 1,3,5-tribromobenzene by using NaOMe. 13) However, in all cases, our achieved yield of 2 was very poor.…”