Model of mouse pancreaticoduodenal transplantation

Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique

“…Despite major progress utilizing in vitro models, the development of animal models is crucial to deepen the knowledge of molecular mechanisms involved in IRI-associated graft alterations following pancreas transplantation. Several pancreas transplantation models have been developed in rodents 5,6 , but only one is reported in mice 7 . The Achilles heel of this highly demanding microsurgical procedure is the low survival rate of 46%.…”