Model for End-Stage Liver Disease (Meld) Score, As a Prognostic Factor for Cirrhotic Patients, Undergoing Hepatectomy for Hepatocellular Carcinoma

Abstract

Background/Aims: To evaluate the ability of the model for end-stage liver disease (MELD) in predicting the post-hepatectomy outcome for hepatocellular carcinoma (HCC). Methods: between the periods from January 2007 to June 2010 in National liver Institute (NLI)-Menoufiya University 60 cirrhotic patients with HCC underwent hepatectomy and the results were retrospectively analysed. MELD score was associated with post-operative mortality and morbidity, hospital stay and 3-year survival. Results: Eleven major and 49 minor resections were performed. Thirty-day mortality rate was 8.3%. MELD ≤ 9 was associated with 2.6% peri-operative mortality vs. 20% when MELD > 9 (P < 0.05). Overall morbidity rate was 53.3%; 36.6% when MELD > 9 vs. 16.6% when MELD ≤ 9 (P < 0.05). Median hospital stay was 18 days [12 days, when MELD ≤ 9 and 22 days when MELD > 9 (P = 0.05)]. Three-year survival reached 51% (66% when MELD ≤ 9; 29% when MELD > 9 (P < 0.01). Conclusion: MELD score seems to predict outcome of cirrhotic patients with HCC, after hepatectomy.