Model construction and thrombolytic treatment of rat portal vein thrombosis
Zixiang Wang,
Chenguang Su,
Zheng Liao
et al.
Abstract:Objective
To construct a stable rat portal vein thrombosis (PVT) model and explore the time window of urokinase thrombolytic therapy on this basis.
Methods
Constructing a rat PVT model by combining anhydrous ethanol disruption of portal endothelium with stasis of blood flow. Forty-eight rats after PVT modeling were divided into control group and experimental group, with 24 rats in each group. The experimental and control groups were given urokinase treatment and saline tail vein injection, respectively. The … Show more
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