Model-based scale-up and reactor design for solvent-free synthesis of an ionic liquid in a millistructured flow reactor

Abstract

Based on kinetic investigations in microreactors, a millistructured plate reactor for a solvent-free ionic liquid synthesis was designed by combining several scale-up concepts to maintain thermal stability.

Entwurf und Betrieb eines Rohrreaktors mit enger Verweilzeitverteilung

“…Eli Lilly für eine Hydrierung mit ca. 12 h Verweilzeit ; d) Wendelrohrreaktor mit jeweils zwei Wicklungen und 180°‐Umlenkungen der Arbeitsgruppe Prof. Röder, Hochschule Mannheim ; e) CFI in Zickzack‐Aufbau für eine Kühlungskristallisation , ; f) Glasreaktor in CFI‐Design , , g) modularer Aufbau eines CFI in Kastenform .…”

Lab‐Scale Microreactor Plant for the Study of Methylations with Liquid Chloromethane

“…This can be used for the optimization of reaction conditions and will provide a basis for a scale-up towards an industrial-scale continuous process. A model-based scale-up with simultaneous solution of mass and energy balances presents a scientifically sound approach to cover the subject of heat transfer [13]. In addition, sufficient residence time and moderate mixing have to be provided since the reaction kinetics indicate a reaction time in the range of several minutes.…”

“…Mass transfer can occur both at the front and end caps of the slugs and in the film layer between the droplet and the capillary wall, depending on the capillary material and the wetting properties of the fluids [7]. Taylor flow and its applications are described in-depth in the literature, e.g.. see [8][9][10][11][12][13][14]. However, the interplay between mass transfer and intrinsic reaction kinetics in the context of the flow pattern has to be investigated.…”

Study on Interfacial Mass Transport and Process Intensification for Ionic Liquid [BMIM]Br Synthesis

“…To implement this solution, it is critical to investigate the behavior of the formed droplets during the neat synthesis of the MIM-based ILs. Such interfacial mass transfer also appears in the microreactors , as well as the traditional mixing tank due to the solubility of alkylating agents in the IL phase.…”