“…Most of the attention is being directed at reducing process variation by various means, such as using feedforward control to reduce run-to-run variation (Leang, Shang-Yi, Thomson, Bombay, & Spanos, 1996;Ruegsegger, Wagner, Freedenberg, & Grimard, 1999), or employing model predictive control (Edgar, Campbell & Bode, 1999). Multivariate statistical methods have also been applied with varying degrees of success (e.g., Chen, Wynne, Goulding, & Sandoz, 2000).…”