Mode of interaction of two fluorinated-hydrogenated hybrid amphiphiles with dipalmitoylphosphatidylcholine (DPPC) at the air–water interface

The influence of salinity on surfactant miscibility in mixed dipalmitoylphosphatidylcholine – perfluorooctadecanoic acid monolayer films

“…Film elasticities for the mixed monolayers ranged from $10 to 130 mN/m at the low surface pressure, to values of $80-420 mN/m for the high surface pressure regime. While it is difficult to find published values for chemically comparable systems, we note that these values are generally higher than the elasticities reported by Hoda et al [15] for mixed DPPC/partially fluorinated ''hybrid" phenylphosphate films, which were typically around 30-40 mN/m and 100-200 mN/m for comparable surface pressures.…”

“…Results of a similar nature have been reported in mixed vesicle (bilayer) systems [24]. Shibata et al have also reported on surfactant miscibility in a number of mixed perfluorocarbon-phospholipid systems [9,15,16,25]. Of particular interest are investigations of a series of perfluorocarboxylic acids (CF 3 (CF 2 )nCOOH) with DPPC on high salinity (0.2 M NaCl) aqueous subphases.…”

“…A significant body of work exists on interactions between biological surfactants and fluorinated surfactants, in part because of the potential deleterious effects surfactant miscibility can have on lung-surfactant mixtures when fluorinated substances are respirated (see [12][13][14][15][16][17][18][19][20][21] for example). Lehmler et al [17,22,23] have carried out a number of investigations of miscibility on binary mixtures of partially fluorinated surfactants and phosphatidylcholines of varying chain length and reported that these monolayer mixtures are often partially miscible (negative deviations from ideal mixing) at the air-water interface, with film components most typically exhibiting an attractive interaction.…”

Stability enhancement effect of normal long-chain alcohols on ion pair amphiphile monolayers at the air/water interface

“…Fig. 1a) exhibited a plateau at π ∼ 15.0 mN/m where the liquid-expanded (LE) and liquid-condensed (LC) phases coexisted, as generally found in double-chained phospholipid monolayer isotherms, such as a dipalmitoyl phosphatidylcholine monolayer isotherm [18,19].…”

Langmuir Monolayer Miscibility of Perfluorocarboxylic Acids with Biomembrane Constituents at the Air-Water Interface

“…Dynarowicz-atka and coworkers systematically investigated the monolayer behavior of FnHm with various degrees of fl uorination 33 37 . Recently, other types of fl uorinated compounds such as long-chain alcohols CF 3 CF 2 n 1 CH 2 m OH, FnHmOH 16, 38 41 , carboxylic acids CF 3 CF 2 n 1 CH 2 m COOH, FnHmCOOH 42 46 , perfluorinated carboxylic acids CF 3 CF 2 n 1 COOH, FnCOOH 47 50 , catanionic surfactants synthesized by equimolar mixing of perfl uorinated and hydrogenated compounds 51 56 , and hybrid-type surfactants covalently combining F-chains with H-moieties 57,58 have been reported.…”