Modality-dependent post-imperative negative variations in schizophrenic patients

The Modality Shift Effect. Further Explorations at the Crossroads

“…Such post-imperative negative variations with a fronto-central maximum often develop long after an imperative stimulus and are the only components that have been repeatedly found to be larger in the ERPs of patients with a schizophrenic disorder than for normals or most psychiatric controls. In a number of studies we have found these late fronto-central negativities to be considerably more pronounced after responses to auditory than to visual stimuli (Cohen, Rist, Finger & Mussgay, 1990). Most likely they reflect a basic uncertainty about response-outcome contingencies or the appropriateness of one's preceding response (cf.…”

“…In line with the literature (cf. Cohen, 1990), patients with schizophrenia had both smaller N1 and smaller P3 amplitudes (F 2 5.09, p < 0.001). In STUDY I1 (FIG.…”

“…This activation extends in time far beyond the motor response and might best be seen as a modality-dependent variant of the post-imperative negative variation (cf. Cohen, 1990). Such post-imperative negative variations with a fronto-central maximum often develop long after an imperative stimulus and are the only components that have been repeatedly found to be larger in the ERPs of patients with a schizophrenic disorder than for normals or most psychiatric controls.…”