Modafinil-Induced Mania in an Elderly Man

Francois, Dimitry; Chelidze, Khatiya

doi:10.4088/pcc.17l02187

Cited by 4 publications

(1 citation statement)

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“…In the case with unipolar depression that we reported here, the patient was using duloxetine 30 mg/day and modafinil 100 mg/day. Both drugs were reported to be associated with mania 25,30 but no previous data were reported on the effects of their combination on mood switching. However, duloxetine and modafinil were prescribed in their lowest effective doses in this case, which significantly decrease the possibility of a manic switch and of a considerable pharmacokinetic interaction even though they cannot be neglected completely.…”

Section: Discussionmentioning

confidence: 99%

Black cohosh associated mania in a patient with unipolar depression

Yalçın

Oğuz

Beştepe

et al. 2020

Int J Psychiatry Med

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Black cohosh ( actaea racemosa, cimicifuga racemosa) a popular complementary medicine, is commonly prescribed as an alternative drug to hormone replacement therapy for the treatment of menopause symptoms and menstrual pain. Studies on the black cohosh’s psychological effects are generally focused on the perimenopausal depression and anxiety; and, its effects have been considered to be affiliated with its serotonergic and dopaminergic activities. We report a patient presenting with acute onset mania associated with black cohosh use, probably due to its psychopharmacological activities on serotonergic and dopaminergic receptors. We suggest that black cohosh must be used cautiously in the patients with history of unipolar depression or bipolar disorder.

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Section: Discussionmentioning

confidence: 99%