Mobile biosafety level (BSL) 2 laboratories deployment: Strengthening the diagnostic facilities in Pakistan with emerging public health challenges and the way forward

Qasmi, Shamsul Arfin; Ikram, Aamer; Tariq, Muhammad; Khadim, Muhammad Tahir; Maqbool, Nabeel Ahmed

doi:10.1016/j.jobb.2023.05.002

Cited by 1 publication

(1 citation statement)

References 11 publications

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“…There are already some 57 BSL-3+ labs ( Kaiser, 2023 ), the safety levels of which are poorly defined ( GBR, 2023 ). There are currently great experiments going on regarding the feasibility of rapid response mobile BSL-2 lab deployment to areas with a public health crisis, but those labs carry additional risks from rogue elements ( Qasmi et al, 2023 ). Or, what about if all BSL-2 labs (which include most labs that work with agents associated with human diseases) suddenly started doing BSL-3 or BSL-4 type work?…”

Section: Discussionmentioning

confidence: 99%

The whack-a-mole governance challenge for AI-enabled synthetic biology: literature review and emerging frameworks

Undheim

2024

Front. Bioeng. Biotechnol.

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AI-enabled synthetic biology has tremendous potential but also significantly increases biorisks and brings about a new set of dual use concerns. The picture is complicated given the vast innovations envisioned to emerge by combining emerging technologies, as AI-enabled synthetic biology potentially scales up bioengineering into industrial biomanufacturing. However, the literature review indicates that goals such as maintaining a reasonable scope for innovation, or more ambitiously to foster a huge bioeconomy do not necessarily contrast with biosafety, but need to go hand in hand. This paper presents a literature review of the issues and describes emerging frameworks for policy and practice that transverse the options of command-and-control, stewardship, bottom-up, and laissez-faire governance. How to achieve early warning systems that enable prevention and mitigation of future AI-enabled biohazards from the lab, from deliberate misuse, or from the public realm, will constantly need to evolve, and adaptive, interactive approaches should emerge. Although biorisk is subject to an established governance regime, and scientists generally adhere to biosafety protocols, even experimental, but legitimate use by scientists could lead to unexpected developments. Recent advances in chatbots enabled by generative AI have revived fears that advanced biological insight can more easily get into the hands of malignant individuals or organizations. Given these sets of issues, society needs to rethink how AI-enabled synthetic biology should be governed. The suggested way to visualize the challenge at hand is whack-a-mole governance, although the emerging solutions are perhaps not so different either.

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Section: Discussionmentioning

confidence: 99%

The whack-a-mole governance challenge for AI-enabled synthetic biology: literature review and emerging frameworks

Undheim

2024

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

Mobile biosafety level (BSL) 2 laboratories deployment: Strengthening the diagnostic facilities in Pakistan with emerging public health challenges and the way forward

Cited by 1 publication

References 11 publications

The whack-a-mole governance challenge for AI-enabled synthetic biology: literature review and emerging frameworks

The whack-a-mole governance challenge for AI-enabled synthetic biology: literature review and emerging frameworks

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