Mo2004 Squeeze Profile -A Novel and Improved Measure of Anal Function Using High-Resolution Anal Manometry

The importance of a high rectal pressure on strain in constipated patients: implications for biofeedback therapy

“…Although others have shown anal sphincter pressures to be higher in healthy men than women, data regarding gender differences in isolated rectal pressure on strain are scarce. A study using conventional manometry did not report any gender differences, while data using high‐resolution manometry have been more conflicting . As we did not include a healthy control group, we can only speculate that men with chronic constipation and defecatory symptoms are more prone than women to adapt a physiological pattern that involves generating abnormally high rectal pressures on strain.…”

“…A study using conventional manometry did not report any gender differences, 18 while data using high-resolution manometry have been more conflicting. [19][20][21] As we did not include a healthy control group, we can only speculate that men with chronic constipation and defecatory symptoms are more prone than women to adapt a physiological pattern that involves generating abnormally high rectal pressures on strain. Notwithstanding, our data suggest that patients with dyssynergic symptoms and high rectal pressure on strain (being men or women)…”