Mo1285 Endoscopic Ultrasound-Guided Liver Biopsy Versus Percutaneous and Trans-Jugular Liver Biopsy for Evaluation of Liver Parenchyma

Shahshahan, Mohammad; Gertz, Henning E.; Fakhreddine, Ali; Datta, Anuj; Eysselein, Viktor E.; Reicher, Sofiya; French, Samuel W.; Hou, Linda A.

doi:10.1016/j.gie.2017.03.1134

Cited by 5 publications

(3 citation statements)

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“…However, EUS-E could become an interesting tool to complete the examination in the case of patients without apparent biliary tract conditions on EUS, who underwent EUS because of altered liver function tests. [ 25 26 ]…”

Section: Methodsmentioning

confidence: 99%

EUS liver assessment using contrast agents and elastography

et al. 2018

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Transabdominal-US is the first-line imaging modality used to assess the whole liver parenchyma and vascularization; EUS assessment of the liver is incomplete and is not sufficient to rule out the presence of focal liver lesions. On the other hand, due the high diagnostic yield in detecting very small (< 1 cm) lesions, EUS is considered complementary to radiological imaging techniques for the investigation of liver parenchyma. Scarce data are available regarding the investigation of liver parenchyma using both EUS-elastography (EUS-E) and CH-EUS. The aim of this review is to evaluate the clinical role of image enhancement techniques, namely EUS-E and contrast harmonic-EUS (CH-EUS), for the evaluation liver diseases. Despite a potential interest for the application of EUS-E in the assessment of liver diseases, available evidence relegates this technique only to research areas, such as the differential diagnosis between benign and malignant focal liver lesions and the quantification of liver fibrosis in diffuse parenchymal diseases. With the future introduction of EUS shear-wave elastography, interesting data can be obtained for the assessment of liver fibrosis during real-time EUS evaluation. The usefulness of CH-EUS for the evaluation of liver disease is limited by the intrinsic EUS ability to explore only the left lobe and a small part of the right lobe. CH-EUS could be used to increase the diagnostic ability of EUS for the detection and characterization of small lesions and for guiding tissue sampling. Targeting EUS-guided treatments with either EUS-E or CH-EUS might represent potential future applications.

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Section: Methodsmentioning

confidence: 99%

EUS liver assessment using contrast agents and elastography

et al. 2018

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“…Five comparator studies were included in this meta-analysis and a total of 656 patients were enrolled-EUSLB (n = 301); PCLB (n = 176); and TJLB (n = 179). 14,[40][41][42][43] A PRISMA flow chart of search results is shown in Fig. 1.…”

Section: Included Study and Patient Characteristicsmentioning

confidence: 99%

Endoscopic Ultrasound-Guided, Percutaneous, and Transjugular Liver Biopsy: A Comparative Systematic Review and Meta-Analysis

et al. 2020

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Background/Aims: Percutaneous liver biopsy (PCLB) or transjugular liver biopsy (TJLB) have traditionally been performed to obtain a sample of hepatic tissue; however, endoscopic ultrasound-guided liver biopsy (EUSLB) has become an attractive alternative. The aim of this study was to compare the efficacy and safety of EUSLB, PCLB, and TJLB. Methods: Search strategies were developed in accordance with PRISMA and MOOSE guidelines. Major outcomes included the following: adequacy of biopsy specimens (i.e., complete portal triads [CPT], total specimen length [TSL] in mm, and length of longest piece [LLP]) in mm), and rate of adverse events. Only studies comparing all biopsy approaches (i.e., EUSLB, PCLB, and TJLB) were included. Results: Five studies (EUSLB [n=301]; PCLB [n=176]; and TJLB [n=179]) were included. Biopsy cumulative adequacy rates for EUSLB, PCLB, and TJLB were 93.51%, 98.27%, and 97.61%, respectively. Based on the subgroup analysis limited to EUS biopsy needles in current clinical practice, there was no difference in biopsy adequacy or adverse events for EUSLB compared to PCLB and TJLB (all p>0.050). A comparison of EUSLB and PCLB revealed no difference between specimens regarding both CPT (p=0.079) and LLP (p=0.085); however, a longer TSL (p<0.001) was observed. Compared to TJLB, EUSLB showed no difference in LLP (p=0.351), fewer CPT (p=0.042), and longer TSL (p=0.005). Conclusions: EUSLB appears to be a safe, minimally invasive procedure that is comparable to PCLB and TJLB regarding biopsy specimens obtained and rate of adverse events associated with each method.

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“…If histological confirmation is needed, EUS-guided LB is a safe technique with a diagnostic yield for liver parenchymal disorders such as liver cirrhosis, primary sclerosing cholangitis, autoimmune hepatitis and NAFLD between 91 % and 100 % 62 63 64 65 66 67 68 69 70 71 72 73 , which is at least comparable to percutaneous or transjugular routes 16 74 75 . Few complications have been reported with this technique.…”

Section: Introductionmentioning

confidence: 99%

The role of EUS in diagnosis and treatment of liver disorders

et al. 2019

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Background and aim Transabdominal ultrasound (US), computed tomographic scanning (CT) and magnetic resonance imaging (MRI) are established diagnostic tools for liver diseases. Percutaneous transhepatic cholangiography is used to perform hepatic interventional procedures including biopsy, biliary drainage procedures, and radiofrequency ablation. Despite their widespread use, these techniques have limitations. Endoscopic ultrasound (EUS), a tool that has proven useful for evaluating the mediastinum, esophagus, stomach, pancreas, and biliary tract, has an expanding role in the field of hepatology complementing the traditional investigational modalities. This review aimed to assess the current scientific evidence regarding diagnostic and therapeutic applications of EUS for hepatic diseases.

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Mo1285 Endoscopic Ultrasound-Guided Liver Biopsy Versus Percutaneous and Trans-Jugular Liver Biopsy for Evaluation of Liver Parenchyma

Cited by 5 publications

References 0 publications

EUS liver assessment using contrast agents and elastography

EUS liver assessment using contrast agents and elastography

Endoscopic Ultrasound-Guided, Percutaneous, and Transjugular Liver Biopsy: A Comparative Systematic Review and Meta-Analysis

The role of EUS in diagnosis and treatment of liver disorders

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