Mn2O3 nanoparticle-porous silicon nanocomposite based amperometric sensor for sensitive detection and quantification of Acetaminophen in real samples

Ahmed, Jahir; Faisal, M.; Alsareii, Saeed A.; Jalalah, Mohammed; Alsaiari, Mabkhoot; Harraz, Farid A.

doi:10.1016/j.ceramint.2022.09.067

Cited by 19 publications

(8 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results agree with those reported in the literature and verify that NAPQI is easily decomposed at low pH. 14,32 APAP oxidation mechanism on hydrophilic SWCNH/GCE at pH 1.-The APAP oxidation mechanism at pH 1 is suggested in Scheme 1. The oxidation of APAP on hydrophilic SWCNH/GCE involves 2e − /2H + transfer processes to produce NAPQI.…”

Section: Resultssupporting

confidence: 90%

“…This electrochemical behavior is due to the limited kinetic energy involved in the electrooxidation of APAP. 32 Figure 5b displays the non-linear peak current variations for scan rates of 10−300 mVs −1 , implying that it is not a diffusioncontrolled reaction. Figure 5c reveals that the anodic and cathodic peak currents vary linearly with the scan rate, suggesting that a surface-controlled reaction controls the electrochemical reactions of APAP and p-benzoquinone on hydrophilic SWCNH/GCE.…”

Section: Resultsmentioning

confidence: 99%

“…The higher anodic peak potential is proportional to the logν with the linear regression equation as follows: According to the Laviron equation (Eq. 3), 32 we can estimate the αn value.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Electrochemical Determination of Acetaminophen Using a Hydrophilic Single-Walled Carbon Nanohorn Modified Glassy Carbon Electrode

Weng,

Yang,

et al. 2023

J. Electrochem. Soc.

View full text Add to dashboard Cite

A simple and novel electrochemical sensor based on a hydrophilic single-walled carbon nanohorn (SWCNH) modified glassy carbon electrode (GCE) was designed for the determination of acetaminophen (APAP). The hydrophilic SWCNH/GCE was characterized using transmission electron microscopy, Raman spectroscopy, X-ray diffractometer, and X-ray photoelectron spectroscopy. This proposed sensor exhibits remarkable performance for the electrocatalytic detection of APAP. The hydrophilic SWCNH/GCE shows a good differential pulse voltammetry response at APAP concentration from 100 to 1000 M with sensitivity and a detection limit of 2.63 µAM-1cm-2 and 1 M. Regarding the reaction mechanism, the hydrophilic SWCNH/GCE could easily electro-catalyze APAP oxidation to form N-acetyl-p-benzoquinone-imine (NAPQI). Then NAPQI is rapidly degraded to p-benzoquinone in solutions of 0.1 M Na2SO4 and 0.05 M H2SO4 at pH 1.

show abstract

Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Electrochemical Determination of Acetaminophen Using a Hydrophilic Single-Walled Carbon Nanohorn Modified Glassy Carbon Electrode

Weng,

Yang,

et al. 2023

J. Electrochem. Soc.

View full text Add to dashboard Cite

show abstract

“…AA molecules release electrons to the conduction-band of the Yb 2 O 3 .CuO@rGO nanocomposite that ultimately enhance the conductivity of the Yb 2 O 3 .CuO@rGO/GCE sensor and, hence, an enhanced CV response can be obtained. In comparison to other AA sensors, the Yb 2 O 3 .CuO@rGO/GCE sensor demonstrated a greater sensitivity for AA detection ( Table 1 ) [ 13 , 17 , 39 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 ].…”

Section: Resultsmentioning

confidence: 99%

Low Overpotential Amperometric Sensor Using Yb2O3.CuO@rGO Nanocomposite for Sensitive Detection of Ascorbic Acid in Real Samples

et al. 2023

Self Cite

View full text Add to dashboard Cite

The ultimate objective of this research work is to design a sensitive and selective electrochemical sensor for the efficient detection of ascorbic acid (AA), a vital antioxidant found in blood serum that may serve as a biomarker for oxidative stress. To achieve this, we utilized a novel Yb2O3.CuO@rGO nanocomposite (NC) as the active material to modify the glassy carbon working electrode (GCE). The structural properties and morphological characteristics of the Yb2O3.CuO@rGO NC were investigated using various techniques to ensure their suitability for the sensor. The resulting sensor electrode was able to detect a broad range of AA concentrations (0.5–1571 µM) in neutral phosphate buffer solution, with a high sensitivity of 0.4341 µAµM−1cm−2 and a reasonable detection limit of 0.062 µM. The sensor’s great sensitivity and selectivity allowed it to accurately determine the levels of AA in human blood serum and commercial vitamin C tablets. It demonstrated high levels of reproducibility, repeatability, and stability, making it a reliable and robust sensor for the measurement of AA at low overpotential. Overall, the Yb2O3.CuO@rGO/GCE sensor showed great potential in detecting AA from real samples.

show abstract

“…Sensitivity was calculated using the equation, sensitivity = S/Aeff [61], where Aeff stands for the surface area of the modified electrode (0.0493 cm 2 ) as stated in the electronic supplemental materials [63]. Equations were used to calculate LOD and LOQ are: LOD = 3.3(Sb/S) and LOQ = 10(Sb/S), respectively [64]; here, Sb (0.000403) stands for RSD related to five blank responses and S stands for calibration curve's slope. Electrocatalytic performance is dependent on two variables: (i) increase in Ipa and (ii) decreased Epa.…”

Section: Sensor Parameters Determinationmentioning

confidence: 99%

Low Overpotential Amperometric Sensor using Yb2O3.CuO@rGO Nanocomposite for Sensitive Detection of Ascorbic Acid in Real Samples

Ahmed¹,

Faisal²,

Algethami³

et al. 2023

Preprint

View full text Add to dashboard Cite

The ultimate objective of this research work is to design a sensitive and selective electrochemical sensor for efficient detection of ascorbic acid (AA), a vital antioxidant found in blood serum that may serve as a biomarker for oxidative stress. To achieve this, we utilized a novel Yb2O3.CuO@rGO nanocomposite (NC) as the active material to modify the glassy carbon working electrode (GCE). The structural properties and morphological characteristics of the Yb2O3.CuO@rGO NC were investigated using various techniques to ensure their suitability for the sensor. The resulting sensor electrode was able to detect a broad range of AA concentrations (0.5 - 1571 µM) in neutral phosphate buffer solution with a high sensitivity of 0.4341 µAµM-1cm-2 and a reasonable detection limit of 0.062 µM. The sensor's great sensitivity and selectivity allowed it to accurately determine the levels of AA in human blood serum and commercial vitamin C tablets. It demonstrated high levels of reproducibility, repeatability, and stability, making it a reliable and robust sensor for the measurement of AA at low overpotential. Overall, the Yb2O3.CuO@rGO/GCE sensor showed great potential in detecting AA from real samples.

show abstract

Mn2O3 nanoparticle-porous silicon nanocomposite based amperometric sensor for sensitive detection and quantification of Acetaminophen in real samples

Cited by 19 publications

References 64 publications

Electrochemical Determination of Acetaminophen Using a Hydrophilic Single-Walled Carbon Nanohorn Modified Glassy Carbon Electrode

Electrochemical Determination of Acetaminophen Using a Hydrophilic Single-Walled Carbon Nanohorn Modified Glassy Carbon Electrode

Low Overpotential Amperometric Sensor Using Yb2O3.CuO@rGO Nanocomposite for Sensitive Detection of Ascorbic Acid in Real Samples

Low Overpotential Amperometric Sensor using Yb2O3.CuO@rGO Nanocomposite for Sensitive Detection of Ascorbic Acid in Real Samples

Contact Info

Product

Resources

About