MMRV Vaccine Associated Transient Neutropenia: Description of Two Cases

Abstract

Post-vaccination neutropenia is not uncommon. The risk of thrombocytopenia following MMR vaccination is 1 in 30,000 to 1 in 40,000 vaccinated children. The clinical course of these cases is usually transient and benign.

Adverse events following Measles-Mumps-Rubella and varicella immunization: A safety profile analysis and comparison of different vaccination schedules based on the Italian Pharmacovigilance Network in the Veneto Region

“…According to the literature, also neutropenia is not uncommon following live vaccine administration ( Muturi-Kioi et al, 2016 ). An Italian case report described two cases of transient neutropenia following MMRV immunization that occurred in one-year-old children ( Giannotta, 2018 ). According to our study only two cases were found; one case had recovered at follow-up, while the other one had no follow-up available.…”