The relationship between the pionium lifetime and the ππ scattering lengths is established, including the sizable electromagnetic corrections. The bound state formalism that is used is that of constraint theory which provides a covariant three-dimensional reduction of the Bethe-Salpeter equation. The framework of generalized chiral perturbation theory allows then an analysis of the lifetime value as a function of the ππ scattering lengths, the latter being dependent on the quark condensate value.The possible measurement of the pionium (π + π − atom) lifetime with a 10% precision in the DIRAC experiment at CERN [1] is expected to allow a determination of the combination (a 0 0 − a 2 0 ) of the ππ scattering lengths with 5% accuracy; here, a I 0 is the strong interaction (dimensionless) S-wave scattering length in the isospin I channel. The strong interaction scattering lengths a 0 0 and a 2 0 have been evaluated in the literature in the framework of chiral perturbation theory (χP T ) to two-loop order of the chiral effective lagrangian [2][3][4]. Therefore, the pionium lifetime measurement provides a high precision experimental test of chiral perturbation theory predictions.The nonrelativistic formula of the pionium lifetime in lowest order of electromagnetic interactions was first evaluated by Deser et al. [5]. It reads:where ∆m π = m π + −m π 0 and ψ +− (0) is the wave function of the pionium at the origin (in x-space).A precise comparison of the theoretical values of the strong interaction scattering lengths with experimental data necessitates, however, an evaluation of the corrections of order O(α) (α being the fine structure constant) to the above formula. Such an evaluation was recently done by several authors. In the frameworks of quantum field the-ory and χP T , three different methods of evaluation have led to the same estimate, of the order of 6%, of these corrections [6][7][8][9]. The first method uses a three-dimensionally reduced form of the Bethe-Salpeter equation (constraint theory approach) and deals with an off-mass shell formalism [6,7]. The second method uses the Bethe-Salpeter equation with the Coulomb gauge [8]. The third one uses the approach of nonrelativistic effective theory [9].The pionium lifetime, with the sizable O(α) corrections included in, can be represented as:where Re M 00,+− is the real part of the onmass shell scattering amplitude of the process π + π − → π 0 π 0 , calculated at threshold, in the presence of electromagnetic interactions and from which singularities of the infra-red photons have been appropriately subtracted [10]; the factor γ represents contributions at second-order of perturbation theory with respect to the nonrelativistic zeroth-order Coulomb hamiltonian of the bound state formalism. The explicit expressions