The seasonal distribution of the phytoplankton and their relationship with environmental parameters of Lake Ketence was studied in monthly intervals in two stations between October 2016 and September 2017. A total of 93 taxa belonging to 8 divisions were identified, and 11 taxa belonging to 4 different divisions (Chlorophyta, Bacillariophyta, Euglenozoa, Miozoa) dominated the phytoplankton in different periods of the study. Main nutrients (NO3-N, NO2-N, TP, Si), some other parameters (T, EC, secchi disk depth), and organic content of the lake had strong impacts on the distribution of phytoplankton assemblages. Although biomass values varied and indicated very good to bad water quality during the studied period, especially the prevalence of chlorophytes such as Tetraedron minimum which prefer high nutrient and euglenoids such as Euglena clavata, Euglena rubra, Phacus longicauda and Trachelomonas oblonga that grew extremely well under high organic content has confirmed that Lake Ketence is eutrophic.